Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ANAPC2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID29882
Official gene symbolANAPC2
Full nameanaphase promoting complex subunit 2
Aliases,APC2,RP11-350O14.5,
Gene summaryA large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. [provided by RefSeq]
LocationChromosome: 9   Locus: 9q34.3
Gene position140083057 - 140069236  Map Viewer
Gene orientationminus
Gene size13822 bp
Gene sequence
OMIM ID606946