Entrez gene ID | | 2990 |
Official gene symbol | | GUSB |
Full name | | glucuronidase, beta |
Aliases | | ,BG,FLJ39445,MPS7, |
Gene summary | | This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. There are many pseudogenes of this locus in the human genome. |
Location | | Chromosome: 7 Locus: 7q21.11 |
Gene position | | 65447301 - 65425671 Map Viewer |
Gene orientation | | minus |
Gene size | | 21631 bp |
Gene sequence |
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OMIM ID | | 611499 |
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