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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SNX15 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID29907
Official gene symbolSNX15
Full namesorting nexin 15
Aliases,HSAF001435,
Gene summaryThis gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. This gene encodes two transcript variants encoding distinct isoforms. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q12
Gene position64794910 - 64808044  Map Viewer
Gene orientationplus
Gene size13135 bp
Gene sequence
OMIM ID605964