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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IL19 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID29949
Official gene symbolIL19
Full nameinterleukin 19
Aliases,IL-10C,MDA1,NG.1,ZMDA1,
Gene summaryThe protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q32.2
Gene position206972215 - 207016325  Map Viewer
Gene orientationplus
Gene size44111 bp
Gene sequence
OMIM ID605687