Entrez gene ID | | 29969 |
Official gene symbol | | MDFIC |
Full name | | MyoD family inhibitor domain containing |
Aliases | | ,HIC, |
Gene summary | | This gene product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization; p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq] |
Location | | Chromosome: 7 Locus: 7q31.1-q31.2 |
Gene position | | 114562209 - 114659970 Map Viewer |
Gene orientation | | plus |
Gene size | | 97762 bp |
Gene sequence |
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