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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for A1CF (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID29974
Official gene symbolA1CF
Full nameAPOBEC1 complementation factor
Aliases,ACF,ACF64,ACF65,APOBEC1CF,ASP,MGC163391,RP11-564C4.2,
Gene summaryMammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 10   Locus: 10q11.23
Gene position52645435 - 52566325  Map Viewer
Gene orientationminus
Gene size79111 bp
Gene sequence