Entrez gene ID | | 29974 |
Official gene symbol | | A1CF |
Full name | | APOBEC1 complementation factor |
Aliases | | ,ACF,ACF64,ACF65,APOBEC1CF,ASP,MGC163391,RP11-564C4.2, |
Gene summary | | Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 10 Locus: 10q11.23 |
Gene position | | 52645435 - 52566325 Map Viewer |
Gene orientation | | minus |
Gene size | | 79111 bp |
Gene sequence |
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