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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TBX21 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID30009
Official gene symbolTBX21
Full nameT-box 21
Aliases,T-PET,T-bet,TBET,TBLYM,
Gene summaryThis gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q21.32
Gene position45810610 - 45823485  Map Viewer
Gene orientationplus
Gene size12876 bp
Gene sequence
OMIM ID604895