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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GZMA (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3001 Official gene symbol GZMA Full name granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) Aliases ,CTLA3,HFSP, Gene summary Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. [provided by RefSeq] Location Chromosome: 5   Locus: 5q11-q12 Gene position 54398474 - 54406080  Map Viewer Gene orientation plus Gene size 7607 bp Gene sequence >GZMA:4992833..5000439:Length=7607 AGATTTTCAGGTTGATTGATGTGGGACAGCAGCCACAATGAGGAACTCCTATAGATTTCT GGCATCCTCTCTCTCAGTTGTCGTTTCTCTCCTGCTAATTCCTGAAGGTAAGACTGATTC TTCTCATTTCCATTATGACCATGAAGCAAAATGGAGCAGACTTTCAATGAACTTTTGGCA ATATTACCTTCCTATACTGAAAGAAGATGTTTTCCCCCAAGCCTTATAATGTTTAGCCAG GCACAATGGCACATGCCTGTAGTCCCAGCTACTAGGAACGCTGAGGTGGAAGGATCACTT GAGCGCAGGAGTTTGAGTCCAGGCTGGGCGACATAGTGAGACCCTGTCTCTATTTTTTTT TTTTAAATAGCATTCTTTCTTGGATTTTAAATATGTCTGTATTTTAGAAAAAAAAATCTT TTCTTCTCATAATTATTTTGCAAAAGATAGCAGAACCACCAATGCTTATTGCTGCCAATT TGTAACTTGAAAATTGCCAAAAAGGACAATGTAAAAATGAGTTAACAAAACTCTCTTGTT CGTAAAACAAATAGTACCTTCCAGGAAAGGAATAGTGGCAACTTAGTCAGCTCAGCCTTT CCTGCTGCAGAAAATGCATAGATAAAGACAATTAAGACAAATCTGACCTAGACACCAAAA GTGAATCAGGAATTATTAGAATTTTTATACTTATTTCTCTGGTCTAGAGACTCTTTGGCA ATAAATTAAGGCGTGAGGCCAGTTCCCTCATTAACCCTTTGGGTGTGCTATAGTATTTTT TATTAAGCTAATTTTTTGTCTACCAAATGGTAACCAATATTTCTGCTTTTGTGTGAGTTG AGCATGCATGGGTTAAAATGCTGTATAATTCATGGTATTACCACTGAAAGGGTGACAGCT CTTGGGGAGCTCTAGATTTCCCTTGAAGAACCTGCTAGGAAGTGAGGACTACTCTCAAGC TGTGGCAATATGGAGCCAGCCACGGTTTTTCCCAGGATTCATCAGCTTTTGGAGGCAGGG ACTTATGTAATAACCTGCCTTGCCAGGAATTCCCAAAGAACTCTGGTTTATCATATTTAG GTGCATATCTGGTTTATGCACCTAAATATGAGAAGACTTTGGGAGGCTGAGGTGGGTGTT TCACAAGGTCAAGAGATGGAGACCATCTTGGCCAACATGGTGAAACCTTGTCTCCACTAA AAAAACAAAAATTAGCTGGGTATGGTGGCACGTGCCTGTAATCCCAGCTACGCAGGAGGC TGAGGCAGGAGAATCGCTTGAACCAGAGAGTTGGAGGCTGCAGTGAGCTAAGATCGTGCC ACTGCACTCCAGCCTGGTGACAGAGCGAGACTCTGTCTCAAAAAAAAAACAAAAAAGAGA GAGAGAGAGAAGAAATATAAAAATAACAAGGCTGCAGGACATTTGGGACAAAGGTTGGCT ATGTTATAAGCAGGGCATAGTATGACTATATTCAGGCATGTTAAATCCTCCATAACAGAA AAACACAGGGCAGATAAATCCAGCCATATCTTTTCTTCAAAGGAAAACAACAAAAGCAAC CTGCTGTGCTCCTCTTTGTTTCCTGTGTTCAGAGAGGGCAGTGTGGGCCCATATAAGGAA CAGACAGCAAAGCAAGGCACAGTTGAAATCTATCTGTACATGAATCACCCTAGGAAAATT GGGATTGGGTGAAGGTCTTTTGTTTCTATAAGCTCTTTACCCTTTTGTTTCTAGAGCCTA GAATTTCTTCCTCCCAGTTTCCTTTTTAAAAGCAGAGACCTCTGCTTTTTCAAATCACAC TAGCCACATTTCATGTGGTCACTCTCCTCCTTGCTCTTACCCTCATCAAATCTTACGAAA GGCTTCTATAGCTGTCATTAATACTTGCCTGTGAATTTGGCAATGACTTAGTCCTAATTA TGGAACAAGAGGCACTGTGCCCTATTCAAGAAACCATGAGTCTCAGCAAAACTATTTTGG GAGAATCCAAGAACATCTGGTGCAGGAGGTGGAGCACTCGGAGTGTATCACTAAGACATA AGGTTCTCTCTATCTGCATGTATGGTTTGCCTTGTGTTTAGTTCTCACTGTTCCTTAACA ATGGGTCTCTACTTCAAGACTATCATCAAGGAAATGTCACTTAGGCAGAATTCTTGGCAT ATGGTATCTTCTCTCTTCTCTTCCCTATCTCATTGGAAAAGACCTTAGATTAAACCCCAT GGTTTGGTCTAGAGATTGAAGGGGAGGTGCAATCGATGTTATTTTCTTAACTTATGAGTG AGAACAGTGCAGTTTAATAACCAAAAGTCTCATAATGACCAAAGGACTGAGGGGTAGGGT CACAGCTAAACGATGCTAATATCGGTTCATAAGCTATATTTTTGCAATGGCTTGGGGTTA AAAGGGAAGTTATGAGGCTTCTAAAAGTCTTATCTATTTCCCCCAAATTAATAGTTAGCC AAAAAGGGTGGGAGCACTTGAGGTTGTCACTACCACTGGCATTTCCTGCAGCAACTGTTG ATGGTAAAGACCAAGGCAGAGCTTTCTGCCCTGGGGCCTGAGGTTGCTGGTTTGTGACAT CCAGCCTAATGATCCTGGAACAGTCAATGGCCTCGCTTCTGTGGGTGGAAAAACAGGACC CTAGAGTCCAACAGGAATAGGATTTGCATCAGATGTCTGCGGGTCTACATAGAGTAAAAG CAGGGGAAATGCTCTCATCCAGACTTCCTCTCTGAGTGCAAAAAGCATGGCTGGTCTTAG AAACATGACTTTGTGTAGAGCTCTTTGGGGGTGAGCACCAATCTGATTTGTCTTTTTCCA TTGAACAGATGTCTGTGAAAAAATTATTGGAGGAAATGAAGTAACTCCTCATTCAAGACC CTACATGGTCCTACTTAGTCTTGACAGAAAAACCATCTGTGCTGGGGCTTTGATTGCAAA AGACTGGGTGTTGACTGCAGCTCACTGTAACTTGTAAGTGCCTGGGTTTTTAAAAAAAAG TTTGTAAAGATACTCTAATTTGGGGAAACATTAATAAAAAGAGTAGGCCGGGCACAGTGG CTTACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGTGGATCACATGAGGTCAGG AGTTTGAGACTAGCCTGGCCAACATGGTGAAACCCCATCTCTATTAAAAATACAAAATTA GCCAGGCGTGGTGGCGCATGCCTGTAATCCCAGCTACTTTGGAGGCTGAGGCAGGAGAAT TGTTTGAACCTAGGAGGCAGAGGTTGCAGTGAGCCGAGATCGCACCATTGCACTCCAGCC TGGGCAACGAGAGTGAGACTCCATCTCAAAATAAAATAAAATAAAATAAATAAAATAAAA TAAAATAAATAAAATAAAATAAAATAAAATAAAATAAAATAAAATAAAATAAAATAAAAT AAAATAAATAAAATAAAATAAAATAAAATAAAATAAAATAAAATAAAATAAATAAAATAA AATAAAATAAATAAAATAAAATAAAATAAAATAAAATAAAATAAAATAAAATAAAAAAAT AAAATAAAATAAAATAAAATAAAATAAAATAAAAAATAAAATAAAATAAAATAAAATAAA ATAAAATAAAATAAAATAAATAAAATAAAATAAAATAAAATAAAATAAAATAAAATATAA AATAAAATAAAATATAAAATAAAATAAAATAAATAAAATAAAATAAAGTAGATCCCACTG AAGCCATGGGAGGTTCATATGTATCTTCACATCGCTTAAGTCTTTGGGCACTTGCTTGAG CCTAAAAGGAAGTTAGGCCCACACTTGCCACAAAGAATCAGGCAATGAGGAAGCAGCATC CACAAGCTCTTTCTGTACATCTCCACTGAGCCATTGGGTACAGGTGCTGCAGAGCTTTGC TTCTGTCATGACTGCGTGACCAGGTAGAATTAGCCTCAGCATGGAAGGGTGAAACTTTCA GTGCCCCCTCAGAGCCCTGGGTGCAACCATCAAGTACAGAAAGCTTGTGTCCAATGACCT TCTTGTATGCCTCCGTGAATTCCTCTCACATCTTTGGCCATCTCTTCACTCCTGTCGACC ACTACATTCAAACCTCTTCCCAGGCCTGGTCTTTTCCTACTCTCTAAATCAAGCCTCTAA ACCTAGGCCATTCAATATGATAGGCACTAGCTACATGTAGCTATGTAAATTTCAATCAAT TAAAGTTAAATAAAATCTCAAATTAGTTCCTCAGTTGCACTAGCCACATTTCAAGTCCTC AGTAGCCACATGTGGCTAGTGCAGATTCATAGAACATTTCATCATAAAAATATGCTCTAC TGGAAAGCACTGTTCTAAGGTCTTTTTCTTTTATTTTTTAATTATTTACTTTTTATTGAC ATATAATAGTTGCACATATGTTGGGGATACATGTGACCATTTAAGTGAGACTAATCTCAG CTGATGTAATGGAAAAGAGGCAGTGTGCATAATCTGGTTGGTGTAGTTTATACTAGGTTA TGAATGATAGCCTTAATCCAATCATCAGTACATCAGAAAGCATTTTGATTTTGATAACCA AAATGAACCTTTAAGAGAAAAAAAGACTCCTGGACCCCTCCTTCAGACCACCATCCCTTC AACACACTCAATGCCAAGCACACTCAATGCCAAGCAAATAGGGTCCTCCATGGGGCAATC TGTTTCTGAAAGTTTTCCCATTTGAGTTTGTTGTTTTCTTGAAAAGATCCCTTCAGTGCA TTACTTTACAACTATTGGCTGCTTTTTGCTTCTGTCTCTGGACTACTGAGATCTTTGCTT CCCATCACAGCTAATAAGTAATTCTCCATCACAGCTAAATAAGGCAGGGGTAGGGGGCAG ATAAGCACAAGACTTGGCTTTGCTGCCATGGAATTCTCTTGTTTTTCAATGAACCTAGTT TAGCTTTTTATAAATAAGCTGGTGATGATGATGATGACGATAAATTCATAAACATTCTTT TATTCATAAACATTCTTTTATTCTTTAAAGCACACATTTTCTTTCTGAGCCACAAAGAAA TCTCCCCACCTCCATATTTACAAATGGGACAATGAAACTGATCAGTATATATGCTCAACT GCCAATACAAAGAATAAATCCAGTAAATAATGTTGTGTCTGTTCTCAGGAACAAAAGGTC CCAGGTCATTCTTGGGGCTCACTCAATAACCAGGGAAGAGCCAACAAAACAGATAATGCT TGTTAAGAAAGAGTTTCCCTATCCATGCTATGACCCAGCCACACGCGAAGGTGACCTTAA ACTTTTACAGGTACGTATCTTTGATTGTCTTCTCAAAAGTCATAGAACCTTCTACAATCT GGCCGCCGACGTGAAAACCTTTCCTTGGTGCCCCTGTTGTAAAAACTCACAATAAAGAGG ATCCTGAAATTTTGGACTATAATTTAAAATGTAAATATTTATCTTATCCCATTAACACTT TATGTTTTTCTTCCAACAGCTGATGGAAAAAGCAAAAATTAACAAATATGTGACTATCCT TCATCTACCTAAAAAGGGGGACGATGTGAAACCAGGAACCATGTGCCAAGTTGCAGGGTG GGGCAGGACTCACAATAGTGCATCTTGGTCCGATACTCTGAGAGAAGTCAATATCACCAT CATAGACAGAAAAGTCTGCAATGATCGAAATCACTATAATTTTAACCCTGTGATTGGAAT GAATATGGTTTGTGCTGGAAGCCTCCGAGGTGGAAGAGACTCGTGCAATGTAAGTAAAAT AAGATCCCACGTTTCAGCTATTGAATTAAGTCATGCAGACAGAGAAAATGTAATGTCATG CTTTGTTTTGTCATGGCACTGGCTTCTACAGGATCCTAGAGCTTTTTGAAATAAGTTTAA TAAAACCCCAGTCAAATAAATGAATGCTCGCAGCTCAAGTGAGTCATTAATCAAAAATAA GAAGTTCACTGCTAGTGCATGGGGTGACCTACTACATATTTTTGATTTTTTACAAAAATT ACTAAGAAGCAATGTTTGGTCTCATTTTTCATGTTAACATACGTAGATCTAAACTTGAAG ATATACAACACTTATGAGAGCTGAAGTCAGGGTTCCTCAAGGCCACTCAGTACTCTTTCC CCATTTCAGTACATTCCCTCTCCTTCCCCACTACGTTCCTCTGCCATTTAACATCGGCAT GTCTGAAATGTCTGTCAAGCCTGGCTGAATATTTCCAGCCAGACCCCATAGCTTCCTAGA GCTTAGTTTAATCTGCAGCAAACTTCAAAGCATGACTCATACCAGAAAATGTGTAAGCTT CCATCCTAGAACCCCCTGAGAAGAGGTGGGATAGGGCCATGCTTAAAGATGAGAATAGAA GAAACATTTTGCAGATTTTTAAACTGAGTACTACCTTGCATTTCTCATTTGTCCCAAAGA CCCTATAGAGCCTTACCTGAAGAAGGGTGTGCAGTATGCATGGTTTGGCAGTTACCAGAG ACTGAGAAATCCAAAGGTCTCTGTCCTTCCCTAGATCTATGTCTTGCTTTCAGAACCAAA GCTAGCCAAATCCCAGGAAAAGAAAACATTTGTCTTCAGTACCTGTCCACTTTCTCTTCT CTGCCCTAGTTCCCCCATTCCCTCCCTTGTCCACCACCCTGGGTTCCCAGGAACCCAGAA CCTTCATGCTTTTGGAACCCACATGCAGCATCCTAAGGCCACGGCAGCATCCCAAGACGC TAGTCCCCATCCCACCAGCCACCCGCCACCACCGAAACTTGGCAATCCTTGCCTGTTCTC TCAACACCCTGGAATTGGCTATTGATGAATTAAACCTAAAGGACTAATTCTGCAAATGCC AGTTACTGTAACAGGCAGGGGAAATAAACCTGTTCAGGGAGGATCCCGGGTTCCAACATG GTTCTTTATTTCATATCTTTATAAGGCCAACTTTTGCCTGAAAGGGACTGATTTGGTTTT GTTTCTTTTGGAAGGCAATTATCTGCTAGAAGAACCACAAAACATAGTGTTTATTCTTTG CTTCAATGTATCATCTGCATTTGACTATTTTGCCCCTTGAGTTATTAAGCATTTTGAGAA AACGACAAATAAACAGGAGACTTTCCTTTCCAAAAGCAGAGCAATAGTCTCAAAATTAGC TGATAACATGTACAAGTTTCACTTCGATTTTCACTGGCTCATAAATAAACCAAGTGAACC AATTCAAAAATATTAAAATATTTCCAAACATTTTAATTTTTAAAATTAAAGCACTATCTT CAATTAAGTCAAGGTTGGTCTTAACTGCATATTAAATGCTGCAGAATTTCTTCCATTTCA CTAGTGGTAATGCTGAACACTGACCCCACACCCTACCCCTCTTGTTTTCCTCCAGGGAGA TTCTGGAAGCCCTTTGTTGTGCGAGGGTGTTTTCCGAGGGGTCACTTCCTTTGGCCTTGA AAATAAATGCGGAGACCCTCGTGGGCCTGGTGTCTATATTCTTCTCTCAAAGAAACACCT CAACTGGATAATTATGACTATCAAGGGAGCAGTTTAAATAACCGTTTCCTTTCATTTACT GTGGCTTCTTAATCTTTTCACAAATAAAATCAATTTGCATGACTGTA OMIM ID 140050