| Entrez gene ID | | 3003 |
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| Official gene symbol | | GZMK |
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| Full name | | granzyme K (granzyme 3; tryptase II) |
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| Aliases | | ,TRYP2, |
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| Gene summary | | This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq] |
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| Location | | Chromosome: 5 Locus: 5q11-q12 |
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| Gene position | | 54320107 - 54329960 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 9854 bp |
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| Gene sequence |
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| OMIM ID | | 600784 |
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