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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for H2AFZ (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3015 Official gene symbol H2AFZ Full name H2A histone family, member Z Aliases ,H2A.z,H2A/z,H2AZ,MGC117173, Gene summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq] Location Chromosome: 4   Locus: 4q24 Gene position 100871512 - 100869244  Map Viewer Gene orientation minus Gene size 2269 bp Gene sequence >H2AFZ:complement(25416965..25419233):Length=2269 ATTGGTGGGATGAGCAATCCGAGTTCCCGGATGAGGGAACATTCTGCAGTATAAAGGGAG CAGGGAAGGCGGGAGACAGCGCAGTTTGAATCGCGGTGCGACGAAGGAGTAGGTGGTGGG ATCTCACCGTGGGTCCGATTAGCCTTTTCTCTGCCTTGCTTGCTTGAGCTTCAGCGGAAT TCGAAATGGTAAACTTCGCAGAGACGCTCGATGACTCCGCGGGTTTTTGCCGGCGAGAGA AAAACCCGTTACACAGAGGGATGGGGGTGAAGTGGCGACGGTTGGGAACGCGCGGAGACA GGATTTAGAAGAGTGGGGGGAGGTGTTTTGTCGGCTGCTAGCGGAGCAGCCTCGGATCTC GCGGCGGGCGGCGACGGTTGGGTGGCGCGCGCAGCGCCGCTGGGGGCCGGCGGGCGGAGG CGCGCGGCCGTGGCGAGCGCGCGGCGGGGGGCGAACGGGCGGGGTCGCCCCTGCGGCGCG CCGCGGGCCGGAGACCCCGGCAGGGTGCGGGGACGCGCTCGCGGCGGGACGCGCCGCGGT GGGGGATGGGCGCGCCGCCTTGGTAATTCTATATTCTCCGTTCCTCCTCCGCTCGCGGGC GTGTGCGCGCCGCAGGCTGGCGGTAAGGCTGGAAAGGACTCCGGAAAGGCCAAGACAAAG GCGGTTTCCCGCTCGCAGAGAGCCGGCTTGCAGGTCAGTAGTTGTTCGTGCAGTCTGGGA GTCATGATGTTTTTCTTTGCATTTCCTTTTTTGTTATTCATCGCTCTCGATGGGCGTTTT GTGTATGCGTGGGTGATGCGGTGTCGCGACTTGGGCTGCCCATACGATAAATATGGGGGG GAGGAATCACGTGTTTCGATGTCGGGACGCGTTGCTGCGCCCGTGCCCCTTGCTTTGGCG CGCATATAATTTCCCCATCTCTAGTTCTCATTTTTGTGCATTTATGTTTGTGTATGCTTA AAATTTAAGTTCCCAGTGGGCCGTATTCATCGACACCTAAAATCTAGGACGACCAGTCAT GGACGTGTGGGCGCGACTGCCGCTGTGTACAGCGCAGCCATCCTGGAGTACCTCACCGCA GAGGTAAATGGGTGAACGCCTATAATCCGGAGAAGGTTTGGGGGGCGGGGAGGCGGCAAG AGGGAAGGAGGAAAGTGATGCAAGAAAACTCCCAGGCCCTGAACGCGGCGAGAGGCCTAA GAGAACGCTAGAGGGAGCTGGTGTTCAACAAGGATCCTACTGAGCTTGAGTTCTCTGCTC TTGGAATTAAAATTGCGTGCCCCCTGTATATCTTGCCAGTCAGATAGTGAGGAACGATTC CAGTTGGTAGATCTGCGTTTGTGAGGGTTTTATTCTGTTCTCTGAATCTTGGCCAAAGGA AAGTTGGAAGGCAACTGACAGATTCTGCCTTTTAGGTACTTGAACTGGCAGGAAATGCAT CAAAAGACTTAAAGGTAAAGCGTATTACCCCTCGTCACTTGCAACTTGCTATTCGTGGAG ATGAAGAATTGGATTCTCTCATCAAGGCTACAATTGCTGGTGGTGGTATGTTAACTTCTA ACATTTTAAAAAATTTCTTCAGAGGAAGGAATTTTTTGCTGCTTTTAATTAGTTTTTCCA GGAGAGGAAATTTAAGTATATTTTCAATGATGGAAGTATGGTTGTATCATGAAATTTGAT TTATATGTATAACTCAATGAATTTTTACTTCATACTTGAGCTGCATGTTTTTAAAGATAC CTTTCAAGTTGAACAGTATACACTTTCTTGGTTTCAAATACTGTGATTTTTTAAAAAATC TTAAGTAGAATTAATTCCTGTCACTCTCCTAGGTGTCATTCCACACATCCACAAATCTCT GATTGGGAAGAAAGGACAACAGAAGACTGTCTAAAGGATGCCTGGATTCCTTGTTATCTC AGGACTCTAAATACTCTAACAGCTGTCCAGTGTTGGTGATTCCAGTGGACTGTATCTCTG TGAAAAACACAATTTTGCCTTTTTGTAATTCTATTTGAGCAAGTTGGAAGTTTAATTAGC TTTCCAACCAACCAAATTTCTGCATTCGAGTCTTAACCATATTTAAGTGTTACTGTGGCT TCAAAGAAGCTATTGATTCTGAAGTAGTGGGTTTTGATTGAGTTGACTGTTTTTAAAAAA CTGTTTGGATTTTAATTGTGATGCAGAAGTTATAGTAACAAACATTTGGTTTTGTACAGA CATTATTTCCACTCTGGTGGATAAGTTCAATAAAGGTCATATCCCAAAC OMIM ID 142763