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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ERVW-1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 30816 Official gene symbol ERVW-1 Full name endogenous retroviral family W, env(C7), member 1 Aliases ,ENV,ENVW,ERVWE1,HERV-7q,HERV-W-ENV,HERV7Q,HERVW,HERVWENV, Gene summary Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq] Location Chromosome: 7   Locus: 7q21-q22 Gene position 92107229 - 92097694  Map Viewer Gene orientation minus Gene size 9536 bp Gene sequence >ERVWE1:complement(30130537..30140072):Length=9536 ATGGGAGCTGTTTTCATGCTATTTCACTCTATTAAATCTTGCAACTGCACTCTTCTGGTC CATGTTTCTTACGGCTCGAGCTGAGCTTTTGCTCACCGTCCACCACTGCTGTTTGCCACC ACCGCAGACCTGCCGCTGACTCCCATCCCTCTGGATCCTGCAGGGTGTCCGCTGTGCTCC TGATCCAGCGAGGCGCCCATTGCCGCTCCCAATTGGGCTAAAGGCTTGCCATTGTTCCTG CACGGCTAAGTGCCTGGGTTTGTTCTAATTGAGCTGAACACTAGTCACTGGGTTCCATGG TTCTCTTCTGTGACCCACGGCTTCTAATAGAACTATAACACTTACCACATGGCCCAAGAT TCCATTCCTTGGAATCCGTGAGGCCAAGAACTCCAGGTCAGAGAATACGAGGCTTGCCAC CATCTTGGAAGCGGCCTGCTACCATCTTGGAAGTGGTTCACCACCATCTTGGGAGCTCTG TGAGCAAGGACCCCCCGGTAACATTTTGGCAACCACGAACGGACATCCAAAGTGGTGAGT AATATTGGACCACTTTCACTTGCTATTCTGTCCTATCCTTCCTTAGAATTGGAGGAAAAT ACCGGGCACTTGTCGGCCAGTTAAAAACGATTAGTGTGGCCACCGGACTTAAGACTCAGG TGTGAGGCTATCTGGGGAAGGGCTTTCTAACAACCCCCAACCCTTCTGGGTTGGGGACTT GGTTTGCCTCAAGCCAGCTTCCACTTTCAGTTTTCTTGGGGAAGCCGAGGGCCGACTAGA GGCAGAAAGCTGTCGTCCTGAACTCCCGGCAGTAGCCGGTTGAGATCATGGTGTAGCCAG AAGTCTCAACAGTCGCCCATGCATGCACCCCTATCTTTCCTTCTGACCCATACCTCCTGG GTCCCAACCACAACTTTCTTCAAAGTGTAGCCCCAAAATTCTCCTTACCTCTGAATATAC TTCCTCTGATCCCTGCCTCCTAGGTACTATTGGTTCAGACTTCCATTTCCTCTAGCAAGT TGTATCTCCAAAGGGATCTAAGGAAGCTCTGCGCTGCGTCCTTAGGCACCTAGGCTATAA CCCAGGGAGTCTTATCCCTGGTGTCCCTCCCAATTTAGGCATACAGCTCTTGACATGGGC AGTTATGTAGGACCCACTCCCCACCACCCTTGCCAGGGCCCCAAGTTTGTAAATGGCTGA GGGAAAAGAGAGACAGAGGAGAGAGAGAGAAATGGAGGAGAAAGAGAGAGAGACAGAGAG GAGAGAGAGACAGTGAGAGAGACAGAAGAGAGAGAGAGACAAAGAGGAGAGAGAGAGAGT CAAAGAGAGAAAGAAAGAGAAAGAAATAGTAAAAAACAGTGTGCCCTATTCCTTTAAAAG CCAGGGTAAATTTAAAACCTGTACTTGATAATTGAAGGTCTTCTCTGTGACCCTATAGCA CTCCAATCCACTTTGTGGTCAGTGTAAATAAGAGCATAGGCCGAAAGCACTGAGGCCATT GACAACCCGTAGCTTCCCTATCAAAAATCCTTAACCCAGTAACCCGCAGATGGACCAAAT GCATTCAGTCGGTAGCGCAACTGCTTTGCTAAAAGTAGAAAAGTAACTTTTAGAGGAAAC CTCATTGTGAGCACACCTCACCTGTTCAGAATTATTCTAATAAAAAAAGCAAAAAGGTAG CTTACTAACTCAAAAATCTTAAAGTATGGGGCTATTCTGTTAGAAAAAGGTAATGTAACT CCAACCACTGATAATTCCCTTAACCCAGCAGATTTCCTAACGGGATTTAAATCTTAATTA CCATACAAAGGTCCGACCAGACCTAGGCGGAACTCCCTTCAGGACAGGACGATAGATGGT TCCTCCCAGGTGATTGAGGAAAAAAACCACAATGGGTATTCAGTAATTGATACGGGGACT CTTGTGGAAGCAGAGTTAGAAAAATTGCCTAATAACTGGTCTCCTCAAACGTGTGAGCTG TTTGCACTCAGCCAAGCCTTAAAGTACTTACAGAATCAAAAGACTATCTCAATCCTGATT CAAAAGGTTAGCTACACCCTCTCTGTAATGCATTTGCATAAGAACTTGTTTATGGGAATG CATCTTGATGGGGCAGCTGGGTTGTTATAAAATAGGAACCCAGCCCAGCTCTAGGACTCA CCCCTGAGCGCAAAGGCAATGTTGGGCATGCTGGTAAAGGACCACTAGAATCCAGCAGCC CAGACCCCTTTCTTTGTGGTCAAGAAAGGCGGGAAAAGGGGTGCAGGACTGCTACATCGG TAAGCATAACTAATCCGATAAACAGAGGTCCATGGGTGGTTACGCACCCTGGAAAGGAAC TCACCCCTGAGCACAAAGGCAATGTTGGGCACGCTGGTAAAGGACCACTAGAATCCAGCA GCCTGGACCCCTTTCTTTGTGGTCAAGAGAGGCAGGAAAACAGGTGCAGGACTGCAACAT CAGTGAGCATAACTAATTCGATAAGCAGAGGTCCATGGGTGGTGATGCACCCTGGAAAGA ATAAGCATTAGGACCATAGAGGACACTCCAGGACTAAAGCTCATCGGAAAATGACTAGGG TTGCTGGCATCCCTATGTTCTTTTTTCAGATGGGAAACGTTCCCCGCAAGACAAAAACGC CCCTAAGACGTATTCTGGAGAATTGGGACCAATTTGACCCTCAGACACTAAGAAAGAAAC GACTTATATTCTTCTGCAGTGCCGCCTGGCACTCCTGAGGGAAGTATAAATTATAACACC ATCTTACAGCTAGACCTCTTTTGTAGAAAAGGCAAATGGAGTGAAGTGCCATAAGTACAA ACTTTCTTTTCATTAAGAGACAACTCACAATTATGTAAAAAGTGTGATTTATGCCCTACA GGAAGCCTTCAGAGTCTACCTCCCTATCCCAGCATCCCCGACTCCTTCCCCAACTAATAA GGACCCCCCTTCAACCCAAATGGTCCAAAAGGAGATAGACAAAAGGGTAAACAGTGAACC AAAGAGTGCCAATATTCCCCAATTATGACCCCTCCAAGCAGTGGGAGGAAGAGAATTCGG CCCAGCCAGAGTGCATGTGCCTTTTTCTCTCCCAGACTTAAAGCAAATAAAAACAGACTT AGGTAAATTCTCAGATAACCCTGATGGCTATATTGATGTTTTACAAGGGTTAGGACAATT CTTTGATCTGACATGGAGAGATATAATGTCACTGCTAAATCAGACACTAACCCCAAATGA GAGAAGTGCCACCATAACTGCAGCCTGAGAGTTTGGCGATCTCTGGTATCTCAGTCAGGT CAATGATAGGATGACAACAGAGGAAAGAGAATGATTCCCCACAGGCCAGCAGGCAGTTCC CAGTCTAGACCCTCATTGGGACACAGAATCAGAACATGGAGATTGGTGCTGCAGACATTT GCTAACTTGTGTGCTAGAAGGACTAAGGAAAACTAGGAAGAAGTCTATGAATTACTCAAT GATGTCCACCATAACACAGGGAAGGGAAGAAAATCCTACTGCCTTTCTGGAGAGACTAAG GGAGGCATTGAGGAAGCGTGCCTCTCTGTCACCTGACTCTTCTGAAGGCCAACTAATCTT AAAGCGTAAGTTTATCACTCAGTCAGCTGCAGACATTAGAAAAAAACTTCAAAAGTCTGC CGTAGGCCCGGAGCAAAACTTAGAAACCCTATTGAACTTGGCAACCTCGGTTTTTTATAA TAGAGATCAGGAGGAGCAGGCGGAACAGGACAAACGGGATTAAAAAAAAGGCCACCGCTT TAGTCATGACCCTCAGGCAAGTGGACTTTGGAGGCTCTGGAAAAGGGAAAAGCTGGGCAA ATTGAATGCCTAATAGGGCTTGCTTCCAGTGCGGTCTACAAGGACACTTTAAAAAAGATT GTCCAAGTAGAAGTAAGCCGCCCCCTCGTCCATGCCCCTTATTTCAAGGGAATCACTGGA AGGCCCACTGCCCCAGGGGACAAAGGTCCTCTGAGTCAGAAGCCACTAACCAGATGATCC AGCAGCAGGACTGAGGGTGCCTGGGGCAAGCGCCATCCCATGCCATCACCCTCACAGAGC CCTGGGTATGCTTGACCATTGAGGGCCAGGAGGTTGTCTCCTGGACACTGGTGCGGTCTT CTTAGTCTTACTCTTCTGTCCCGGACAACTGTCCTCCAGATCTGTCACTATCTGAGGGGG TCCTAAGACGGGCAGTCACTAGATACTTCTCCCAGCCACTAAGTTATGACTGGGGAGCTT TATTCTTTTCACATGCTTTTCTAATTATGCTTGAAAGCCCCACTACCTTGTTAGGGAGAG ACATTCTAGCAAAAGCAGGGGCCATTATACACCTGAACATAGGAGAAGGAACACCCGTTT GTTGTCCCCTGCTTGAGGAAGGAATTAATCCTGAAGTCTGGGCAACAGAAGGACAATATG GACGAGCAAAGAATGCCCGTCCTGTTCAAGTTAAACTAAAGGATTCCACCTCCTTTCCCT ACCAAAGGCAGTACCCCCTCAGACCCAAGGCCCAACAAGGACTCCAAAAGATTGTTAAGG ACCTAAAAGCCCAAGGCCTAGTAAAACCATGCAGTAACCCCTGCAGTACTCCAATTTTAG GAGTACAGAAACCCAACAGACAGTGGAGGTTAGTGCAAGATCTCAGGATTATCAATGAGG CTGTTGTTCCTCTATAGCCAGCTGTACCTAGCCCTTATACTCTGCTTTCCCAAATACCAG AGGAAGCAGAGTGGTTTACAGTCCTGGACCTTCAGGATGCCTTCTTCTGCATCCCTGTAC ATCCTGACTCTCAATTCTTGTTTGCCTTTGAAGATACTTCAAACCCAACATCTCAACTCA CCTGGACTATTTTACCCCAAGGGTTCAGGGATAGTCCCCATCTATTTGGCCAGGCATTAG CCCAAGACTTGAGCCAATCCTCATACCTGGACACTTGTCCTTCGGTAGGTGGATGATTTA CTTTTGGCCGCCCATTCAGAAACCTTGTGCCATCAAGCCACCCAAGCGCTCTTCAATTTC CTCGCTACCTGTGGCTACATGGTTTCCAAACCAAAGGCTCAACTCTGCTCACAGCAGGTT ACTTAGGGCTAAAATTATCCAAAGGCACCAGGGCCCTCAGTGAGGAACACATCCAGCCTA TACTGGCTTATCCTCATCCCAAAACCCTAAAGCAACTAAGGGGATTCCTTGGCGTAATAG GTTTCTGCCGAAAATGGATTCCCAGGTATGGCGAAATAGCCAGGTCATTAAATACACTAA TTAAGGAAACTCAGAAAGCCAATACCCATTTAGTAAGATGGACAACTGAAGTAGAAGTGG CTTTCCAGGCCCTAACCCAAGCCCCAGTGTTAAGTTTGCCAACAGGGCAAGACTTTTCTT CATATGTCACAGAAAAAACAGGAATAGCTCTAGGAGTCCTTACACAGATCCGAGGGATGA GCTTGCAACCTGTGGCATACCTGACTAAGGAAATTGATGTAGTGGCAAAGGGTTGACCTC ATTGTTTACGGGTAGTGGTGGCAGTAGCAGTCTTAGTATCTGAAGCAGTTAAAATAATAC AGGGAAGAGATCTTACTGTGTGGACATCTCATGATGTGAATGGCATACTCACTGCTAAAG GAGACTTGTGGCTGTCAGACAACTGTTTACTTAAATGTCAGGCTCTATTACTTGAAGGGC CAGTGCTGCGACTGTGCACTTGTGCAACTCTTAACCCAGCCACATTTCTTCCAGACAATG AAGAAAAGATAAAACATAACTGTCAACAAGTAATTTCTCAAACCTATGCCACTCGAGGGG ACCTTTTAGAGGTTCCTTTGACTGATCCCGACCTCAACTTGTATACTGATGGAAGTTCCT TTGTAGAAAAAGGACTTCGAAAAGTGGGGTATGCAGTGGTCAGTGATAATGGAATACTTG AAAGTAATCCCCTCACTCCAGGAACTAGTGCTCAGCTAGCAGAACTAATAGCCCTCACTT GGGCACTAGAATTAGGAGAAGAAAAAAGGGCAAATATATATACAGACTCTAAATATGCTT ACCTAGTCCTCCATGCCCATGCAGCAATATGGAAAGAAAGGGAATTCCTAACTTCTGAGA GAACACCTATCAAACATCAGGAAGCCATTAGGAAATTATTATTGGCTGTACAGAAACCTA AAGAGGTGGCAGTCTTACACTGCCGGGGTCATCAGAAAGGAAAGGAAAGGGAAATAGAAG AGAACTGCCAAGCAGATATTGAAGCCAAAAGAGCTGCAAGGCAGGACCCTCCATTAGAAA TGCTTATAAAACAACCCCTAGTATAGGGTAATCCCCTCCGGGAAACCAAGCCCCAGTACT CAGCAGGAGAAACAGAATGGGGAACCTCACGAGGACAGTTTTCTCCCCTCGGGACGGCTA GCCACTGAAGAAGGGAAAATACTTTTGCCTGCAACTATCCAATGGAAATTACTTAAAACC CTTCATCAAACCTTTCACTTAGGCATCGATAGCACCCATCAGATGGCCAAATCATTATTT ACTGGACCAGGCCTTTTCAAAACTATCAAGCAGATAGTCAGGGCCTGTGAAGTGTGCCAG AGAAATAATCCCCTGCCTTATCGCCAAGCTCCTTCAGGAGAACAAAGAACAGGCCATTAC CCTGGAGAAGACTGGCAACTGATTTTACCCACAAGCCCAAACCTCAGGGATTTCAGTATC TACTAGTCTGGGTAGATACTTTCACGGGTTGGGCAGAGGCCTTCCCCTGTAGGACAGAAA AGGCCCAAGAGGTAATAAAGGCACTAGTTCATGAAATAATTCCCAGATTCGGACTTCCCC GAGGCTTACAGAGTGACAATAGCCCTGCTTTCCAGGCCACAGTAACCCAGGGAGTATCCC AGGCGTTAGGTATACGATATCACTTACACTGCGCCTGAAGGCCACAGTCCTCAGGGAAGG TCGAGAAAATGAATGAAACACTCAAAGGACATCTAAAAAAGCAAACCCAGGAAACCCACC TCACATGGCCTGCTCTGTTGCCTATAGCCTTAAAAAGAATCTGCAACTTTCCCCAAAAAG CAGGACTTAGCCCATACGAAATGCTGTATGGAAGGCCCTTCATAACCAATGACCTTGTGC TTGACCCAAGACAGCCAACTTAGTTGCAGACATCACCTCCTTAGCCAAATATCAACAAGT TCTTAAAACATTACAAGGAACCTATCCCTGAGAAGAGGGAAAAGAACTATTCCACCCTTG TGACATGGTATTAGTCAAGTCCCTTCCCTCTAATTCCCCATCCCTAGATACATCCTGGGA AGGACCCTACCCAGTCATTTTATCTACCCCAACTGCGGTTAAAGTGGCTGGAGTGGAGTC TTGGATACATCACACTTGAGTCAAATCCTGGATACTGCCAAAGGAACCTGAAAATCCAGG AGACAACGCTAGCTATTCCTGTGAACCTCTAGAGGATTTGCGCCTGCTCTTCAAACAACA ACCAGGAGGAAAGTAACTAAAATCATAAATCCCCATGGCCCTCCCTTATCATATTTTTCT CTTTACTGTTCTTTTACCCTCTTTCACTCTCACTGCACCCCCTCCATGCCGCTGTATGAC CAGTAGCTCCCCTTACCAAGAGTTTCTATGGAGAATGCAGCGTCCCGGAAATATTGATGC CCCATCGTATAGGAGTCTTTCTAAGGGAACCCCCACCTTCACTGCCCACACCCATATGCC CCGCAACTGCTATCACTCTGCCACTCTTTGCATGCATGCAAATACTCATTATTGGACAGG AAAAATGATTAATCCTAGTTGTCCTGGAGGACTTGGAGTCACTGTCTGTTGGACTTACTT CACCCAAACTGGTATGTCTGATGGGGGTGGAGTTCAAGATCAGGCAAGAGAAAAACATGT AAAAGAAGTAATCTCCCAACTCACCCGGGTACATGGCACCTCTAGCCCCTACAAAGGACT AGATCTCTCAAAACTACATGAAACCCTCCGTACCCATACTCGCCTGGTAAGCCTATTTAA TACCACCCTCACTGGGCTCCATGAGGTCTCGGCCCAAAACCCTACTAACTGTTGGATATG CCTCCCCCTGAACTTCAGGCCATATGTTTCAATCCCTGTACCTGAACAATGGAACAACTT CAGCACAGAAATAAACACCACTTCCGTTTTAGTAGGACCTCTTGTTTCCAATCTGGAAAT AACCCATACCTCAAACCTCACCTGTGTAAAATTTAGCAATACTACATACACAACCAACTC CCAATGCATCAGGTGGGTAACTCCTCCCACACAAATAGTCTGCCTACCCTCAGGAATATT TTTTGTCTGTGGTACCTCAGCCTATCGTTGTTTGAATGGCTCTTCAGAATCTATGTGCTT CCTCTCATTCTTAGTGCCCCCTATGACCATCTACACTGAACAAGATTTATACAGTTATGT CATATCTAAGCCCCGCAACAAAAGAGTACCCATTCTTCCTTTTGTTATAGGAGCAGGAGT GCTAGGTGCACTAGGTACTGGCATTGGCGGTATCACAACCTCTACTCAGTTCTACTACAA ACTATCTCAAGAACTAAATGGGGACATGGAACGGGTCGCCGACTCCCTGGTCACCTTGCA AGATCAACTTAACTCCCTAGCAGCAGTAGTCCTTCAAAATCGAAGAGCTTTAGACTTGCT AACCGCTGAAAGAGGGGGAACCTGTTTATTTTTAGGGGAAGAATGCTGTTATTATGTTAA TCAATCCGGAATCGTCACTGAGAAAGTTAAAGAAATTCGAGATCGAATACAACGTAGAGC AGAGGAGCTTCGAAACACTGGACCCTGGGGCCTCCTCAGCCAATGGATGCCCTGGATTCT CCCCTTCTTAGGACCTCTAGCAGCTATAATATTGCTACTCCTCTTTGGACCCTGTATCTT TAACCTCCTTGTTAACTTTGTCTCTTCCAGAATCGAAGCTGTAAAACTACAAATGGAGCC CAAGATGCAGTCCAAGACTAAGATCTACCGCAGACCCCTGGACCGGCCTGCTAGCCCACG ATCTGATGTTAATGACATCAAAGGCACCCCTCCTGAGGAAATCTCAGCTGCACAACCTCT ACTACGCCCCAATTCAGCAGGAAGCAGTTAGAGCGGTCGTCGGCCAACCTCCCCAACAGC ACTTAGGTTTTCCTGTTGAGATGGGGGACTGAGAGACAGGACTAGCTGGATTTCCTAGGC TGACTAAGAATCCCTAAGCCTAGCTGGGAAGGTGACCACATCCACCTTTAAACACGGGGC TTGCAACTTAGCTCACACCTGACCAATCAGAGAGCTCACTAAAATGCTAATTAGGCAAAG ACAGGAGGTAAAGAAATAGCCAATCATCTATTGCCTGAGAGCACAGCAGGAGGGACAATG ATCGGGATATAAACCCAAGTCTTCGAGCCGGCAACGGCAACCCCCTTTGGGTCCCCTCCC TTTGTATGGGAGCTCTGTTTTCATGCTATTTCACTCTATTAAATCTTGCAACTGCA OMIM ID 604659