Entrez gene ID | | 30818 |
Official gene symbol | | KCNIP3 |
Full name | | Kv channel interacting protein 3, calsenilin |
Aliases | | ,CSEN,DREAM,KCHIP3,MGC18289, |
Gene summary | | This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q21.1 |
Gene position | | 95963072 - 96051825 Map Viewer |
Gene orientation | | plus |
Gene size | | 88754 bp |
Gene sequence |
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OMIM ID | | 604662 |
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