Entrez gene ID | | 308993 |
Official gene symbol | | Sephs2 |
Full name | | selenophosphate synthetase 2 |
Aliases | | MGC156840 |
Gene summary | | This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine (Sec) that is co-translationally incorporated into selenoproteins at in-frame UGA codons, which normally signal translation termination. This protein itself contains a Sec residue in its predicted active site. The 3' UTR of this gene has a stem-loop secondary structure called a selenocysteine insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q36 |
Gene position | | 186535716 - 186538034 Map Viewer |
Gene orientation | | minus |
Gene size | | 2319 bp |
Gene sequence |
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