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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for HLA-DQA2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3118 Official gene symbol HLA-DQA2 Full name major histocompatibility complex, class II, DQ alpha 2 Aliases ,HLA-DXA, Gene summary This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. [provided by RefSeq] Location Chromosome: 6   Locus: 6p21.3 Gene position 32709163 - 32714664  Map Viewer Gene orientation plus Gene size 5502 bp Gene sequence >HLA-DQA2:4155064..4160566:Length=5503 TCCTCACAATTGCTCTACAGCTCAGAGCAGCAACTGCTGAGCCTGCCTTGGGAAGAAGAT GATCCTAAACAAAGCTCTGCTGCTGGGGGCCCTCGCCCTGACTGCCGTGATGAGCCCCTG TGGAGGTGAAGACATTGTGGGTGAGTGCATGAGTGAGGAATGTTCTCTGGAGCTGAAAAA CAGTAAATTAAAGGAAAAGAAAGAGTGCAATTTGCTAAGAAATAGTAGAAATTTCCCAAG GGTCTTTTCAATATTAAGAAATTTTAAAATTATGGCAGTTCCTCCTTTAGGAAACCAGAG CTCCAACCGACTCTCTTTGCTACCTGTGCTATTGGAGTTTACCAAGGACGTTGTTCTGTT TATATTATATCCAGAGACTATAGCCTGGAGGTCTGTGTGGCATTCCATCATGATTGCCTC AAAGACTAGGGATGTTTCCATGAATGGAGTATTTTTTTGTTATTAAAAATTTCTGAACTG TTACTCCCAAATTTCTCTGAACAACTTTTGAAGCTTTTCATATGCCTCCTATAGCATATG TTGGGGTAGATAGTTCCATGAAGTATGTACACTCTATAGATATAAAGAAAGAGGTTCTTT TCTTTCTCTCAGACTTACATTTCCACATGGGAATTGGCACAGGTGGGGAGTAGGTGAAAG AGCCCAGCAGGCTGAATGCCTTCAACAATCATTTTACCACGTGGTAAATGTGGTACTTAC TCTCTGCTACCTCATATATGTCACCTCGCTTATGATCAAATAAAATGGGCATGTAGATAT GCTTTATGAATAGTAAAAACACTAATGTCAACTTTTTTTAACTTATTTCTATTACAGGTA TAACTTCTTATTTTTTCTTTAGCAAAGTAAGGAATATATTTTAAAACTGAGAACTTTATG ATAAAATGCTTGGTAAATTAAATTATTTTATTCTCAAATTGTCAACCCAAATTACTTGTT CTTCACCTTATCTAATGAAGTCTTATAAAGAGAAAAATGGGCAGGCACAGATAATTATTT GGTCCCTTAGTCCCCTCTGCCTTTGTCGTCCATCTCTTCCCACCTCTCTTCATGCATCCC TTTCTCCCTCTTCCCTTTCAGGATCCATCTCTGACTCCCTGCTCCTTTACAGACATGGGC AGTGGGTTTGTAAAACAAAAGTTGGAAAGTCAAATAGTTAAAAGGGGAAGTGAACTGGAA GCTACTCGAAACTTCCACAACCTTATTAACCATAGCTGCTCCCATTCTGATTTTGTTTGG CAGTGGAAGTTTCACCTGCTTCTCCAGAGCACTTGGCTTTTTTGTTTCAAATTTCCTTTC TTCAACCTCACACCAGAGTGCCCCGGTCAGGCTCGACTTATCCATTAGGAACAGTGTGGG CAGTGAAGGGGACCCTCCAAACTGTAAAGCTACAAGAGAACGTTTTAACTCCTTTTAAAA TTAGAAGAAAAATGAAGTTTTACAGTCTATGAAAATGTTTTAACTTTTTTTTTTTTTTTT GACGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCACGATCTCCGCTCACTGCA AGCTCCGCCTCCCAGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTA CAGGCGCCCGCCACTGTGCACGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCAC CGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCATGATCCGCCCGTCTCAACCTCCCA AAGTGCTGGGATTACAGGCGTGATCCACCGCGCCCGGCCTTAACTTTTAATGTAGCCTGG ATTGTATTTGTCTTTATACCAATACAATCAGAAGCTGTAATTTTCCGTATTTTTATGGAG GAAGGCGCCCACAAAAGCAACAGTGCTTGGGGCTCACAAGTCAGAATTCAGCCCTGGGCA TCCCTGATCCTGGGCTTTGCGTGGTTCTGCTACCTGGGTGCCTGTCAGTCTTCCCCAAAA TCTATGTAATTGTCAAAAATTGCAATTGTCATTCAATACACATGTTTGAGCACACAATGA GCTAACTTTTGGGAATTCAAAGATAAAAAATCATGCTGTCTGCCTTGCAGAGGGTGCACA AACCAGTGATGGAAACAGTATGGGGCACAGGAAAGCAGAAGGCCCTGCTGAGCAGGACAC TGGCCCAGCAGAGGCTGAAACTATAAAAATGACTTGGTTCCAGCTGGGCCAGTAGAGTGA TGTCCTCCAGCAACACTTAGCACCCAGGACAAGTACCAGATGAAAAGAAGGATTGCATGT ATTCCACATATATTCATGTTTGAACAAGGAGTCAAAGTTTATTGTAAGGATAAGGAGTCT TTGTTGGTGGCCTGTTAAGTAACCAACCAGGGCAGTCATGCTGGGTAGGGAAGAAGGTGA GCTGGAGGAGGAAAAGACAAACTTGGAGAGCCAGACATTGAGATTCCATTGAGGCGTTGG AGGTCACAACGCGGTCAAAAACATGTTGAGAGGACTTAGCTGCAAAGTTGTTAACTAAGT AGAAACCTCAAGGATGAATTTTAGGATTTCTCCAGGAAATCCTAAAAGATAACTTCTTTC AGGGAGAAAAAACAGACCCTTGCAAAGACATGAAAGGAAATGTAGTTTGGTTTGATTGGC AGATAGTTGTGAAGAATGTCGGACTGTAAGGCTGTCGATATCCTCCTCACAGAATTCCCC AAAGTACATTGTATTTGCTCCCTTACCGACCTGATTCTCCCACTATTCAGTTCATTCCTT GATGCTGTTTTAAGCAACCCCTGCTCTGTCTGACACTTTTGGATGCTCAGTAAATGAGGA AGGAAGGAAGGAAAGATAAAATGGTAAAGGGCTCACACATGTCTTAACAAAAATGTCCAG TTCGGCTCATTTGGCTATACTTCATGGCTGCTGCTCTGCCCTGGCATCCTCGGATAAGCT CGCTGCCCATTAGAGGAAAAAGGGTTTAATTTACCTGAGTCCTCGAGTGAATGTAATTGT TGAATCAGAACACTATAGATATTTAGTAACCTCCTTCAGAGGAAAAAAAAAAGTGGGGGC AATGACAGAAATTAAAAAACCAGTTGAGCTTCCACTTTTCATTTCAGAAGAAATCAGGTG CTCTCCTCTAAGGACCACTACTATTAACAAAACAGAGACCTTAGAAGAATTGTTTATTTG TTATAAATGTATAATGTTGCTATTCTTGTAATAGTCTTTCTTGTACCCTATAATTGTTAG AAGAAATTATTTTAAGTTAATACGTTCCTACATGCTTTTCTTTGGTTTAAAAAAAAAAAA AAAAGGAAACTCTGTGTAGAAAGTGTCCTGTTCTGATCTAGTCCTGACAGGAAACGAAGT ATAATCAACTTGTTATTAACTGAGAGAGAAAACTTAGGAAGCAGAGGGAAATAAACTGAA TCTCTGAGTAAGAAAACTAAATCCTATGATAACTCATTCATTCCTTCCTTTGTTTATTGC AATATTCATCATAAGCTTATGATGTGCCAGGCACTAAGTAGGCACTCAGGAAATAACAGA CGTGTGACGTTCTGCCTTTGTGGAGCATATGTTATAGTGAGAAAGACAGAATCAGTTCTA ACCTGATGACTACCAACGTTAGGCAAGGAGGAAGCAGGTGTTAGGAAGATTGTTCAGGGA CTGTGCCAAAGATGAAGCCCATAATATTTGAAAGTGAGTTTCTTCAATCACTTTCTGTAT TAAGGTTCTTTCTCCCTGTGTTCCACCCTCCTGCTTGTCACCTTCACTCGTCAGCTGACC ATGTTGCCTCCTATGGTGTGAACTTCTACCAGTCTCACGGTCCCTCTGGCCAGTACACCC ATGAATTTGATGGAGACGAGGAGTTCTATGTGGACCTGGAGACGAAAGAGACTGTCTGGC AGTTGCCTATGTTTAGCAAATTTATAAGTTTTGACCCGCAGAGTGCACTGAGAAATATGG CTGTGGGAAAACACACCTTGGAATTCATGATGAGACAGTCCAACTCTACCGCTGCCACCA ATGGTATGTGTCCACCATTCCGCCTCTCTTTACTGAAACTAATCTTTCATACCAAGTTTT ACTCCCTTCTTCTCAAGAGATTTCCAGATCTTCTCATGGTAATTGCTGAAATTTTATCAT CTCCCATCTCTAAAATCACATATTCCCATGTAATACAAGGGTCTTTCCATTATGTATTAA TTCCTACTTTATTAAACATGCCCACAGAGAGAAGGGCACAGGAATAAAGCAGAGGCAATG TGTCGTTGCTCCCAAGCAGAAGGTAAATAAGACCTCTTTGACTATCAGGTGGTGAAATGC TGGTAGGAGGGCTCTTCCAGGATGTAATGCAGAAGCTCATGGCAGAGCTATTCACACTTC ACATCAGTGCTGTTTCCTCACCACAGAGGTTCCTGAGGTCACAGTGTTTTCCAAGTTTCC TGTGACGCTGGGTCAGCCCAACACCCTCATCTGTCTTGTGGACAACATCTTTCCTCCTGT GGTCAACATCACCTGGCTGAGCAATGGGCACTCAGTCACAGAAGGTGTTTCTGAGACCAG CTTCCTCTCCAAGAGTGATCATTCCTTCTTCAAGATCAGTTACCTCACCTTCCTCCCTTC TGCTGATGAGATTTATGACTGCAAGGTGGAGCACTGGGGCCTGGACGAGCCTCTTCTGAA ACACTGGGGTAAGGATGAGTTCCACTACTTCATGGGTTTCTAATAATAGACTTCACTCTT CTCCCTAAGCCTGGGGCCTTGAGTCTTGCAGAGCCAGCCCTCCACCCCATCCCATCCCAC ACACATGCACATGAGCACACTGCACATTCTGACCTCAACAGCTCCACTTTCACAGAGCCT GAGATTCCAGCCCCTATGTCAGAGCTCACAGAGACTTTGGTCTGCGCCCTGGGGTTGTCT GTGGGCCTCATGGGCATTGTGGTGGGCACTGTCTTCATCATCCAAGGCCTGCGTTCAGTT GGTGCTTCCAGACACCAAGGGCTCTTATGAATCCCATCCTGAAAAGGAAGGTAAGATTGA GATTTGTTGGAGCTGAAACCTCAGTATGAGAGGGAGGAAAGTGGGAGGGGGTTGTGGACA TGAATGTGGTTGAAAGTTGTAGGCGAATTGGGAAGTGGCATGATGATCACACAGGAGGCC CCTCAGACCCATCGATCTCATGTCTGTCCTGTTGCAGGTGCATCACCATCTACAGGAGAA GAAGAATGGACTTGCTAAATGACCTAGCACTATTCTCTGGCCTGATTTATCATATCCCTT TTCTCCTCCAAATGTTTCTTCTCTCACCTCTTCTCTGGGACTTAAGGTGCTATATTCCCT CAGAGCTCACAAATGCCTTTCAATTCTTTCCCTGACCTCCTTTCCTGAATTTTTTTATTT TCTCAAATGTTACCTACTAAGGGATGCCTGGGTAAGCCACTCAGCTACCTAATTCCTCAA TGACCTTTATCTAAAATCTCCATGGAAGCAATAAATTCCCTTT OMIM ID 613503