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Gene information for HLF (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3131
Official gene symbolHLF
Full namehepatic leukemia factor
Aliases,MGC33822,
Gene summaryThis gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q22
Gene position53342321 - 53402426  Map Viewer
Gene orientationplus
Gene size60106 bp
Gene sequence
OMIM ID142385