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Gene information for HLA-G (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3135
Official gene symbolHLA-G
Full namemajor histocompatibility complex, class I, G
Aliases,MHC-G,
Gene summaryHLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq]
LocationChromosome: 6   Locus: 6p21.3
Gene position29794756 - 29798899  Map Viewer
Gene orientationplus
Gene size4144 bp
Gene sequence
OMIM ID142871