Entrez gene ID | | 3135 |
Official gene symbol | | HLA-G |
Full name | | major histocompatibility complex, class I, G |
Aliases | | ,MHC-G, |
Gene summary | | HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq] |
Location | | Chromosome: 6 Locus: 6p21.3 |
Gene position | | 29794756 - 29798899 Map Viewer |
Gene orientation | | plus |
Gene size | | 4144 bp |
Gene sequence |
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OMIM ID | | 142871 |
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