Home

Search

Browse

Statistics

User guide

FAQs

Links

Questions

Contribute

Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for AOC2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 314 Official gene symbol AOC2 Full name amine oxidase, copper containing 2 (retina-specific) Aliases ,DAO2,RAO, Gene summary Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants. [provided by RefSeq] Location Chromosome: 17   Locus: 17q21 Gene position 40996609 - 41002724  Map Viewer Gene orientation plus Gene size 6116 bp Gene sequence >AOC2:6270761..6276876:Length=6116 TGTTAGAATTCTGATTTCAGCTCTCAGCATCCACCATGCATCTCAAGATAGTCCTGGCGT TCCTGGCACTGTCCCTCATTACCATCTTTGCCCTGGCCTATGTTTTGCTGACCAGCCCAG GTGGTTCCAGCCAGCCTCCCCACTGCCCCTCTGTATCCCATAGGGCCCAGCCCTGGCCAC ACCCTGGCCAGAGCCAGCTGTTTGCAGACCTGAGCCGAGAGGAGTTGACAGCTGTGATGC GCTTTCTGACCCAGCGGCTGGGGCCAGGGCTGGTGGACGCAGCCCAGGCTCAGCCCTCGG ACAACTGCATCTTCTCAGTGGAGCTGCAGCTGCCCCCCAAGGCTGCAGCCCTGGCCCACC TGGACAGGGGGAGCCCCCCACCTGCCCGGGAGGCACTGGCCATCGTCCTCTTTGGTGGAC AACCCCAACCCAATGTGAGTGAGCTGGTGGTGGGGCCGCTGCCTCACCCCTCGTACATGC GGGATGTGACTGTGGAGCGTCACGGCGGGCCCCTGCCCTATCACCGTCGCCCGGTGCTGA GAGCTGAGTTTACACAGATGTGGAGGCATCTGAAAGAGGTGGAGCTACCCAAGGCACCCA TCTTCCTGTCGTCCACCTTCAACTACAATGGCTCTACCCTGGCAGCTGTGCATGCCACCC CTCGGGGCTTGCGCTCAGGGGACCGAGCTACCTGGATGGCCCTCTACCATAACATCTCAG GGGTTGGTCTTTTCCTTCACCCCGTGGGGCTGGAGCTACTACTGGACCACAGGGCCCTGG ACCCTGCCCACTGGACTGTCCAGCAGGTCTTCTACCTTGGGCACTACTATGCAGACTTGG GCCAGTTGGAACGGGAGTTTAAGTCTGGCCGGTTGGAAGTGGTTAGAGTCCCTCTACCTC CACCAAATGGAGCTTCATCCCTGAGGTCTCGGAACTCTCCAGGTCCTCTTCCCCCTCTTC AGTTCTCGCCCCAGGGTTCCCAGTACAGTGTGCAAGGAAACCTGGTGGTATCCTCCCTCT GGTCATTTACCTTTGGCCATGGGGTGTTCAGCGGCCTGAGGATTTTTGATGTTCGGTTCC AGGGTGAGCGAATAGCCTATGAAGTCAGTGTCCAGGAGTGTGTATCTATCTATGGTGCCG ATTCACCCAAGACGATGCTGACTCGCTATTTGGATAGCAGCTTTGGACTCGGCCGTAACA GCCGAGGCTTGGTGCGGGGAGTGGACTGCCCCTATCAAGCCACGATGGTGGACATCCATA TATTAGTGGGCAAAGGGGCAGTCCAGCTGCTTCCAGGGGCTGTGTGTGTATTTGAGGAAG CCCAGGGACTGCCCCTTCGAAGGCACCACAATTACCTTCAAAATCATTTCTATGGTGGTT TGGCCAGCTCAGCCCTTGTGGTCAGGTCTGTGTCATCTGTGGGCAACTATGACTACATTT GGGACTTTGTGTTGTACCCAAATGGGGCACTTGAAGGGCGGGTCCATGCCACGGGTTATA TCAACACAGCTTTCCTGAAAGGGGGAGAGGAGGGCCTCCTCTTTGGGAACCGTGTGGGGG AAAGAGTGCTGGGAACGGTGCACACACATGCCTTCCACTTCAAGCTGGACCTGGATGTGG CAGGTGAGTGCTGAGGGGATGAGGATGGAGACTTGGGGGCGGGGTCAGGTGGGGTGGAGG GAAGGGAAGGGAATCTCCCAGGTCAAGCTGAAATAACAAGTGGCAAGAGCAGGGTGTTCC AACACCACAGCTCTAGTGGCAACAGGGCAGGGACTGTTTGAGCATATTCAGTGCAGTGAG TCTGGTACTGGGCTACTGGGTATCTGGTAAAAGGTGAAAAGAGTTCCCCCGCCCAGCCCC TCTGACTTGCTATGATTGTGAAACTAGTTTAAATGTAATGGCTGGGCATGATTGCCTTAG CCTCAAGTGACACTGGGTGGGTGAACTGGCCCAATGGGGCTGGAGTTGGAGCACTTTGCT TCTTCCTAATTCTGAGGGTCAGTAGGGGTGGGGAGGGCAGGGTCCTGAGCCGAGGTCGGA AGAAGTCTGTCCAGAGTCTTCAGGGTGGGGGTCGACCTGGGGCTTAGGAAGGAGAGGGTA GCAAAGCTGGGGTTGCTCCCCAGGATAGGGCCACTCCTCATCGGGAGGGCCATCCCATTC CTGTCATCACAGTTGACTCATGGCAGGCACACAGCTTGCTGCAAGTATGGAAAGAGATTT CTCAAGCACAAAGGGCTCAAAGCACACAGAGGACTTGCTGTTCCTGACAGACTTTGTCAA GGACAGAAAGGAACTTACAGACTCACACACTGATCCACAAAGAAAATTAGAAACTCACCA GACCCTCTCCATTTTAAGGGAAACTAAGGAGGGTGGCGGGAGATGGGACAGGAAATGACT GCCCAAGTATAATGCAACATAAACTAGTATTTCTTGTGAAATGTTTTCTTATCCTCAAGT CTAAAGACATGGCACGTGCGTGCCTGCGTGTGTCTCTGTGCATGCACTTGCACTTGTGTT CGCAGTGGTGTGGAGGGTAGGAAGGACTAATAGCATGATTGAAATGATCATATTAACTAG ATTACTCTTTGACATACTTGGATTTTGACTTGTCTTCTGATTGGAAGTTTTTCTTCAGCA TCTTTGGCATTAAAGAGGCTTGTTTTGGGAAGTAACATTTATTGGACCCCTAGCGTGTGC AGCATGGGCTGCTGCTGTGGGCCAGAGAGGCTGTGTCAGGCACCAGCTCACAGGATGGCT GCAGAGGCACCAGCTTCAGTGCAGTGCCTCCCGTGCCAGGTACCTTCATATAGGTCTCGT TGAACTTACAGTCCAGACCTGCAGAAAGTGTATGACCAAGTGCTGAGTTAGGCAGTGCAG GTTATGGATGCTGTAGAATTCCAAGGAACTCCCAGACAAAGGTATGAATGTGCTTGCTTC TGAAAAACACTGACAGTACTTCCCACCTTGCTGAGATCAAAAGTGAAGTCTCAGAGCTGG GAGGAGTATGCAGGGGACCATGGGAAGGGATTGGGTTTTCTTTTTTTGAGGCAGTGTCTC ACTGTCACCCAGGCTGGAGTGCAGCGGTGCAATCACAGGTTACTGCAGCCCTGACCTCCT GGGCTCAAGCAATCCTCCTGCCTCAGCCTCCTTAGTAGCTGGGATGACAGGCATACACTA CCACGCCCAGCTTTTTTTTTTTTTTTGAAGACAGAGTCTCACTCTGTTGCCCAGGCTGGA GCACGGTGGTGCAATCTCAGTTCACCGCAACCTCCACCTCCCAGGTTCAAGCGATTCTTG TGTCTCGGCCTCCAGAGTAGCACACCACCACACCTGGCTAATTTTTTTAAATTATTTATT TATTTAAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTCATCTTGAACTCCCGGTCTC AAGTGATCCACTCGCCTCGGCTTCCCAAAGTGCTGTGAGCTACCATGCCCGGCCTTTTTT TTTTTTTTTTTTTTTTTTTTAAGAGGCAGTGTTTCATTCCGTTACCCCAGCTGGTGTCCA GCACCTGGGTTCAAGGGATCTGCATCACCCTGCCACCAGCCTCCTGAGTTGCAAGCTGCC ACACCCGGCTCAGGAGTCAGTTTTTCAGCTAGCTTCTCCAAGACAAATATCATTATCCCT TTCATAGTTAAAAGAATGTCACTAGTCAGCTGCAAGTGCTTTTCTGTTTATTGGGCACAG CCATAGAACAGCTTTAATTATGCCCAGTGTAGGGATTCAGAAAGTGAATCAGAGAAGCAA ATTGGTCCAGGGACTGTTTGGTAGTCCAGTGCTAATAGAACTTTCTGTAGTGATAGAAAT ATTCCGTATTTGAGCTGTGGCTCTAAACAATAGTCACTAGCCATGTGTGGCAACTGGGCA CTTCAAGTGTGGCTAGTGTGACAGAGGAACTGAATATATATATATATATATATACATATA TATATATATATATATTTTAGACAGAGTCTTGCTCTGTTGCCCAGGCTAGAGTGCAGTGGT GTGACCTCAGCTCATTGCAGCCACAACCTACTGGGCTCAAGCAATCCTCCTACCCCAGCT TCCCAAGTAACTGGGACCACAGGCATGTACCACCATGCCTGGCTGATTTTTTTATTGTTT GTAGAGTCAGGGTTTCACCACGTTGCACAGGCTGGTCTCAAACTCCTGGGCTCACATGAT CCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTGCAGGTGTGAGCCACCTCAGCTGGCCC TAAGTTTTAATTTTCATAGCCACGTGTGGCTAGTGGTTACCCTATCGGATAGGGCAAGTT GGAAGAAGATAGGAGCTTGCTCTTGCCCAGACCTCCTGGCTCCCAGCACAGTGTGCTCTG ATGCTCTCTCTGCCTTTTGTCACACCAGTGCAGTGGACATCATGGGGAAGACAGGGACCT GGCCCAGAGACCTTACCTGGTGTGGAACTCATCTCCTTTCCCTCCCCCTGGCAGGGCTGA AAAACTGGGTGGTAGCTGAAGACGTGGTGTTTAAACCTGTGGCTGCCCCCTGGAACCCGG AGCACTGGCTACAGCGCCCACAGCTGACTCGGCAGGTCCTGGGAAAGGAGGACCTGACAG CTTTTTCCTTGGGAAGCCCCCTACCCCGCTACCTCTACCTGGCTAGCAACCAGACTAATG CGTGGGGTCACCAGCGCGGGTACCGAATCCAGATCCACAGCCCCCTTGGCATACACATAC CCCTGGAGAGTGACATGGAGAGGGCCCTCAGCTGGGGGAGGTGAGGAGGGCCCTGGCCTG GGTGGAAGGAAAGGACAGCCCCTCCCCTGCCCCAGTCCTTGGAGACAAACTCCCTTCCCA CGGCTACCATTCATCCCTGTACCTCCCCTCAAACCCAAGTTAGATACACGGTGGGAAATG GTCTCACACAGAATCGGATCTAAGGGACTCCTGGGCCAGTAAAGGCACTTGACATTTCCC AAAACCACCTTCTTATGATTCCTGGCCAGATACCAGCTTGTGGTGACCCAGAGAAAGGAG GAGGAGTCACAGAGCAGTAGCATCTATCACCAGAATGACATCTGGACACCCACAGTTACC TTTGCTGACTTCATCAACAATGAAACCCTCTTAGGAGAGGTTGGTTGCCCTAGGGACATA GGAAAGGGACACCTGTGGGCATGGCATCTTGGCTGCCCAGCCTCTGGCCAAAGGTTAGAG GGAATGGCTGATTTCCAGTTCGCAGATTCAGAGGCCATGGAGTTTTCTGATGACCAACAC AGGTCATCCCTCCTGGGGTGAGATTAGCTCTGGGACACTGGCTCCCCCCTCTCCCCGCAC AGCTGCTTACATGGATTGCTCCACGTGTTGTATGGGCATGAGGCTGGGGAGAGTGGAAGC CAGGCTGAGACTGGAGGCTGGGATTGTGACTGAAGGGTGGTTCTTTGGGTCACGCTTCCA TAGTCCTCCAGCTCCTCCTTCTTCTTGCAGGATCTGGTGGCTTGGGTCACAGCCAGCTTC CTGCACATTCCCCATGCCGAGGACATCCCAAACACAGTGACTCTGGGGAACAGAGTTGGC TTCTTGCTCCGACCCTATAACTTCTTTGATGAGGACCCCTCCATCTTCTCCCCTGGCAGT GTCTACTTTGAGAAGGGCCAGGATGCTGGGCTCTGCAGCATCAATCCTGTGGCCTGCCTC CCCGACCTGGCAGCCTGTGTCCCGGACTTACCCCCTTTCTCTTACCACGGCTTCTAGTCC TGAGGGTGTGGCGGGCGGCGTGGTTAGGCACATGTACTTTTCCCTGTTTCTACTTTCTAT TCTCCGTGTTTTTATCACACCTGCTCCCCAGATTCCCACCCCCTCAATGTTCCTCTCACA CGAAACCCCCATCAGTCCCTTTGGTTAATTCTTACTTCCTGTTCATCTCTAAAGTGTTAA ATTATAAAAATGATTTTTAAATATTCAAAGAAAAATATCACAAATCCTACTACTCAGAAA TAGGTGGTCACATTACATCAGACATCTCTTTATGCATGTGCATTCAAAAGGAAGAGTAGA TAGAATTTTGTAAAACAGATGTTGTATGTAATTTATAATAAAAAGTATTAGAGGAA OMIM ID 602268