Entrez gene ID | | 3150 |
Official gene symbol | | HMGN1 |
Full name | | high-mobility group nucleosome binding domain 1 |
Aliases | | ,FLJ27265,FLJ31471,HMG14,MGC104230,MGC117425, |
Gene summary | | Chromosomal protein HMG14 and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.[supplied by OMIM] |
Location | | Chromosome: 21 Locus: 21q22.3|21q22.2 |
Gene position | | 40721047 - 40714241 Map Viewer |
Gene orientation | | minus |
Gene size | | 6807 bp |
Gene sequence |
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OMIM ID | | 163920 |