| Entrez gene ID | | 3159 |
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| Official gene symbol | | HMGA1 |
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| Full name | | high mobility group AT-hook 1 |
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| Aliases | | ,HMG-R,HMGA1A,HMGIY,MGC12816,MGC4242,MGC4854, |
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| Gene summary | | This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq] |
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| Location | | Chromosome: 6 Locus: 6p21 |
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| Gene position | | 34204577 - 34214008 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 9432 bp |
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| Gene sequence |
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| OMIM ID | | 600701 |
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