Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for HNRNPAB (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3182
Official gene symbolHNRNPAB
Full nameheterogeneous nuclear ribonucleoprotein A/B
Aliases,ABBP1,FLJ40338,HNRPAB,
Gene summaryThis gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q35.3
Gene position177631508 - 177638184  Map Viewer
Gene orientationplus
Gene size6677 bp
Gene sequence
OMIM ID602688