| Entrez gene ID | | 320 |
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| Official gene symbol | | APBA1 |
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| Full name | | amyloid beta (A4) precursor protein-binding, family A, member 1 |
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| Aliases | | ,D9S411E,MINT1,X11,X11A,X11ALPHA, |
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| Gene summary | | The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq] |
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| Location | | Chromosome: 9 Locus: 9q13-q21.1 |
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| Gene position | | 72287275 - 72042449 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 244827 bp |
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| Gene sequence |
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| OMIM ID | | 602414 |
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