Entrez gene ID | | 3214 |
Official gene symbol | | HOXB4 |
Full name | | homeobox B4 |
Aliases | | ,HOX-2.6,HOX2,HOX2F, |
Gene summary | | This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17q21-q22 |
Gene position | | 46655743 - 46652869 Map Viewer |
Gene orientation | | minus |
Gene size | | 2875 bp |
Gene sequence |
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OMIM ID | | 142965 |
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