Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for APCS (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID325
Official gene symbolAPCS
Full nameamyloid P component, serum
Aliases,MGC88159,PTX2,SAP,
Gene summaryThe protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q21-q23
Gene position159557616 - 159558661  Map Viewer
Gene orientationplus
Gene size1046 bp
Gene sequence
OMIM ID104770