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Gene information for HRH1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3269
Official gene symbolHRH1
Full namehistamine receptor H1
Aliases,H1-R,hisH1,
Gene summaryHistamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]
LocationChromosome: 3   Locus: 3p25
Gene position11178779 - 11304939  Map Viewer
Gene orientationplus
Gene size126161 bp
Gene sequence
OMIM ID600167