| Entrez gene ID | | 333 |
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| Official gene symbol | | APLP1 |
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| Full name | | amyloid beta (A4) precursor-like protein 1 |
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| Aliases | | ,APLP, |
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| Gene summary | | This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq] |
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| Location | | Chromosome: 19 Locus: 19q13.1 |
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| Gene position | | 36359401 - 36370699 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 11299 bp |
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| Gene sequence |
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| OMIM ID | | 104775 |
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