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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for APOA1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 335 Official gene symbol APOA1 Full name apolipoprotein A-I Aliases ,MGC117399, Gene summary This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. [provided by RefSeq] Location Chromosome: 11   Locus: 11q23-q24 Gene position 116708338 - 116706469  Map Viewer Gene orientation minus Gene size 1870 bp Gene sequence >APOA1:complement(20268885..20270754):Length=1870 AGAGACTGCGAGAAGGAGGTGCGTCCTGCTGCCTGCCCCGGTCACTCTGGCTCCCCAGCT CAAGGTTCAGGCCTTGCCCCAGGCCGGGCCTCTGGGTACCTGAGGTCTTCTCCCGCTCTG TGCCCTTCTCCTCACCTGGCTGCAATGAGTGGGGGAGCACGGGGCTTCTGCATGCTGAAG GCACCCCACTCAGCCAGGCCCTTCTTCTCCTCCAGGTCCCCCACGGCCCTTCAGGATGAA AGCTGCGGTGCTGACCTTGGCCGTGCTCTTCCTGACGGGTAGGTGTCCCCTAACCTAGGG AGCCAACCATCGGGGGGCTTTCTCCCTAAATCCCCGTGGCCCACCCTCCTGGGCAGAGGC AGCAGGTTTCTCACTGGCCCCCTCTCCCCCACCTCCAAGCTTGGCCTTTCGGCTCAGATC TCAGCCCACAGCTGGCCTGATCTGGGTCTCCCCTCCCACCCTCAGGGAGCCAGGCTCGGC ATTTCTGGCAGCAAGATGAACCCCCCCAGAGCCCCTGGGATCGAGTGAAGGACCTGGCCA CTGTGTACGTGGATGTGCTCAAAGACAGCGGCAGAGACTATGTGTCCCAGTTTGAAGGCT CCGCCTTGGGAAAACAGCTAAAGTAAGGACCCAGCCTGGGGTTGAGGGCAGGGGTAGGGG GCAGAGGCCTGTGGGATGATGTTGAAGCCAGACTGGCCGAGTCCTCACCTAATATCTGAT GAGCTGGGCCCCACAGATGGTCTGGATGGAGAAACTGGAATGGGATCTCCAGGCAGGGTC ACAGCCCATGTCCCCTGCAAAGGACAGACCAGGGCTGCCCGATGCGTGATCACAGAGCCA CATTGTGCCTGCAAGTGTAGCAAGCCCCTTTCCCTTCTTCACCACCTCCTCTGCTCCTGC CCAGCAAGACTGTGGGCTGTCTTCGGAGAGGAGAATGCGCTGGAGGCATAGAAGCGAGGT CCTTCAAGGGCCCACTTTGGAGACCAACGTAACTGGGCACTAGTCCCAGCTCTGTCTCCT TTTTAGCTCCTCTCTGTGCCTCGGTCCAGCTGCACAACGGGGCATGGCCTGGCGGGGCAG GGGTGTTGGTTGAGAGTGTACTGGAAATGCTAGGCCACTGCACCTCCGCGGACAGGTGTC ACCCAGGGCTCACCCCTGATAGGCTGGGGCGCTGGGAGGCCAGCCCTCAACCCTTCTGTC TCACCCTCCAGCCTAAAGCTCCTTGACAACTGGGACAGCGTGACCTCCACCTTCAGCAAG CTGCGCGAACAGCTCGGCCCTGTGACCCAGGAGTTCTGGGATAACCTGGAAAAGGAGACA GAGGGCCTGAGGCAGGAGATGAGCAAGGATCTGGAGGAGGTGAAGGCCAAGGTGCAGCCC TACCTGGACGACTTCCAGAAGAAGTGGCAGGAGGAGATGGAGCTCTACCGCCAGAAGGTG GAGCCGCTGCGCGCAGAGCTCCAAGAGGGCGCGCGCCAGAAGCTGCACGAGCTGCAAGAG AAGCTGAGCCCACTGGGCGAGGAGATGCGCGACCGCGCGCGCGCCCATGTGGACGCGCTG CGCACGCATCTGGCCCCCTACAGCGACGAGCTGCGCCAGCGCTTGGCCGCGCGCCTTGAG GCTCTCAAGGAGAACGGCGGCGCCAGACTGGCCGAGTACCACGCCAAGGCCACCGAGCAT CTGAGCACGCTCAGCGAGAAGGCCAAGCCCGCGCTCGAGGACCTCCGCCAAGGCCTGCTG CCCGTGCTGGAGAGCTTCAAGGTCAGCTTCCTGAGCGCTCTCGAGGAGTACACTAAGAAG CTCAACACCCAGTGAGGCGCCCGCCGCCGCCCCCCTTCCCGGTGCTCAGAATAAACGTTT CCAAAGTGGG OMIM ID 107680