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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IAPP (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3375
Official gene symbolIAPP
Full nameislet amyloid polypeptide
Aliases,DAP,IAP,
Gene summaryIslet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. [provided by RefSeq]
LocationChromosome: 12   Locus: 12p12.3-p12.1
Gene position21525802 - 21532914  Map Viewer
Gene orientationplus
Gene size7113 bp
Gene sequence
OMIM ID147940