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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IARS (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3376
Official gene symbolIARS
Full nameisoleucyl-tRNA synthetase
Aliases,FLJ20736,IARS1,ILERS,ILRS,IRS,PRO0785,
Gene summaryAminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs. [provided by RefSeq]
LocationChromosome: 9   Locus: 9q21
Gene position95056038 - 94972625  Map Viewer
Gene orientationminus
Gene size83414 bp
Gene sequence
OMIM ID600709