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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IBSP (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3381
Official gene symbolIBSP
Full nameintegrin-binding sialoprotein
Aliases,BNSP,BSP,BSP-II,SP-II,
Gene summaryThe protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq]
LocationChromosome: 4   Locus: 4q21-q25
Gene position88720702 - 88733601  Map Viewer
Gene orientationplus
Gene size12900 bp
Gene sequence
OMIM ID147563