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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NLRP10 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 338322 Official gene symbol NLRP10 Full name NLR family, pyrin domain containing 10 Aliases ,CLR11.1,NALP10,NOD8,PAN5,PYNOD, Gene summary Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq] Location Chromosome: 11   Locus: 11p15.4 Gene position 7985059 - 7981156  Map Viewer Gene orientation minus Gene size 3904 bp Gene sequence >NLRP10:complement(7921156..7925059):Length=3904 CCTTCCCCCAGATCACCATGGCCATGGCCAAGGCCAGAAAGCCCCGGGAGGCATTGCTCT GGGCCTTGAGTGACCTTGAGGAGAACGATTTCAAGAAGTTAAAGTTCTACTTACGGGATA TGACCCTGTCTGAGGGCCAGCCCCCACTGGCCAGAGGGGAGTTGGAGGGCCTGATTCCGG TGGACCTGGCAGAATTACTGATTTCAAAGTATGGAGAAAAGGAGGCTGTGAAAGTTGTCC TCAAGGGCTTGAAGGTCATGAACCTGTTGGAACTTGTGGACCAGCTCAGCCATATTTGTC TGCATGGTGAGTGTGGAGCGGGGGAAGGGGAGGGCAGGATGGCACTGGGACTCCCCTCCC ACCATGGCATTTCCAGAGCTGCCTGTAGCCTGTACCTTATGCCTTCTGTCACCTTGTCCT CTAGTCCCTGGTGCCCCAGAGTCCTTGGTGGTCTCCACCTGAGGGTTCCAACAACTGTCA GGAGGGGGACTGAGCCAAAGCTGGGATTTATTTAAGAAAAGACTAGCCTTTCTTCCCCAC ATCTTACCTCCAGCTGCAGTGGCAGAGAAGGGGAGAGTCTGAAGAAAGGGTCTTAGAGAC TGGGAGGGTGTTGGTGAAGGGATTTCCACTAACCAGAAGAAATAGCATCAGGATGTAGGG GTCAGACCTGTCCCTAGCTGCTTCCTGGCAAGCTGCTCAGGCGCTTCTAAGTCTTCTGTG GCCCTGATCTCTCAAGGAACCACACTACAGAATGGGTGGTGTGGGACCTCATGGCCTGCT GGTTCTTCCTGTGGGTGCCTGGGGGGAGGGAGGGATCTTTTGGTGCCTTTGCTCCCTCCC ATAGGCTCCTTTCATGCTTGAAAGCTCCTCTGCTACGTACAAATGGGAGGGTTTCATGGA CCCAGAGTCATGGCTCTTTCTGAGAAGCTGTTTTATCTTTAGCATTTGGCTTGTCCTTTC CCAAGAACAGGCTTATCGGCTGGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGG AGGCTGAGACAGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGA AACCCCGTCTCTACTAAAAATACAAAAAAATTAGCCGGGCATGGTGGCGTGCGCCTGTGG TCCCAGCTACACGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGC AGTGAGTCGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAGAGCGAAACTCCATCTCA AAAAAAAAAAAAAAAAAAAAAGAACAGGCTTATCTTAGTCCCTTTGGTATTGCTATAAAG CAATACCTGAGACTGGGTAATTTATAAAGAAAAGAGGTTTATTTGGCTCATGGTTTGGCA GGTGGTACAAGAGGCATATTGTCAACATTGACTTCTGGCGAGGCCTCAGGCAGCTTTCAG TTATGGAAGAAGGCAAGGTCAGAGCTGGTGTGTCACATGGCAAGAGAGGGAGGAAGAGAG AGGGGAGGAGGTGCCAGGCTCTTTAAACAACCAGCTCTTGTGTAGCTAATAGAGCAAGAA CTCGTTCATTACCGTGGGGAGGGCCCCAAGACATTCATGAGGGATTTGCCCCCATGACAA AAACAACTCCCACTAGGCCCTGCCTCCAACATTGGGGATCACATTTCAACCTGAAATTTG GAGGGGATAAACACCCAAACTATATCAAGGCTCCTATCACTTCACCATCCTCAGGCATCC CTTTCCTTTCCCCTCTCTCTGTCCTCACCTCTTCACATGGAGACATTTCACATGAACACT CAGACATTCATGCATTCTCACACAGGCATTTTGCACTTACATGTATTCTTACAGACACAC ACTTGCTGATGCACACTGACATGACTTCCCTCCACAACAGTACATGAAGGTCCACGAGCA CATGTGGATACCAGCATTCATGCACAACTATCCACACACACAGAGCACACCCTTGCACAC TCATACAGATGTGCATATGCATACTGCGCCTGCACACACACACTCATGCACACATACAGT GGCCCCTCCCCATGAAGCCAGAACTATAATCTCAGCAAGATCCAAGTTGGAGACATACAA GAAGACTAATGAGCAGAGTCAGTTTGGAGGGGCCATTTTGCCTTCTAAAATTCCCATTTC ACTACCTAACATCCCATTTGTTTGGCTCAGATTACAGAGAAGTATACCGAGAGCATGTGC GCTGCCTAGAGGAATGGCAGGAAGCAGGAGTCAATGGCAGATACAACCAGGTGCTCCTGG TGGCCAAGCCCAGCTCAGAGAGCCCAGAATCACTTGCCTGCCCCTTCCCGGAGCAGGAGC TGGAGTCTGTCACGGTGGAGGCTCTATTTGATTCAGGGGAAAAGCCCTCACTGGCCCCAT CCTTAGTTGTGCTACAGGGGTCGGCTGGCACTGGAAAGACAACTCTCGCCAGAAAAATGG TGTTGGACTGGGCCACCGGTACTCTGTACCCAGGCCGGTTTGATTATGTCTTTTATGTAA GCTGCAAAGAAGTGGTCCTGCTGCTGGAGAGCAAACTGGAGCAGCTCCTTTTCTGGTGCT GCGGGGACAATCAAGCCCCTGTCACAGAGATTCTGAGGCAGCCAGAGCGGCTCCTGTTCA TCCTGGATGGCTTTGATGAGCTGCAGAGGCCCTTTGAAGAAAAGTTGAAGAAGAGGGGTT TGAGTCCCAAGGAGAGCCTGCTGCACCTTCTAATTAGGAGACATACACTCCCCACGTGCT CCCTTCTCATCACCACCCGGCCCCTGGCTTTGAGGAATCTGGAGCCCTTGCTGAAACAAG CACGTCATGTCCATATCCTAGGCTTCTCTGAGGAGGAGAGGGCGAGGTACTTCAGCTCCT ATTTCACGGATGAGAAGCAAGCTGACCGTGCCTTCGACATTGTACAGAAAAATGACATTC TCTACAAAGCGTGTCAGGTTCCAGGCATTTGCTGGGTGGTCTGCTCCTGGCTGCAGGGGC AGATGGAGAGAGGCAAAGTTGTCTTAGAGACACCTAGAAACAGCACTGACATCTTCATGG CTTACGTCTCCACCTTTCTGCCGCCCGATGATGATGGGGGCTGCTCCGAGCTTTCCCGGC ACAGGGTCCTGAGGAGTCTGTGCTCCCTAGCAGCTGAAGGGATTCAGCACCAGAGGTTCC TATTTGAAGAAGCTGAGCTCAGGAAACATAATTTAGATGGCCCCAGGCTTGCCGCTTTCC TGAGTAGTAACGACTACCAATTGGGACTTGCCATCAAGAAGTTCTACAGCTTCCGCCACA TCAGCTTCCAGGACTTTTTTCATGCCATGTCTTACCTGGTGAAAGAGGACCAAAGCCGGC TGGGGAAGGAGTCCCGCAGAGAAGTGCAAAGGCTGCTGGAGGTAAAGGAGCAGGAAGGGA ATGATGAGATGACCCTCACTATGCAGTTTTTACTGGACATCTCGAAAAAAGACAGCTTCT CGAACTTGGAGCTCAAGTTCTGCTTCAGAATTTCTCCCTGTTTAGCGCAGGATCTGAAGC ATTTTAAAGAACAGATGGAATCTATGAAGCACAACAGGACCTGGGATTTGGAATTCTCCC TGTATGAAGCTAAAATAAAGAATCTGGTAAAAGGTATTCAGATGAACAATGTATCATTCA AGATAAAACATTCAAATGAAAAGAAATCACAGAGCCAGAATTTATTTTCTGTCAAAAGCA GCTTGAGTCATGGACCTAAGGAGGAGCAAAAATGTCCTTCTGTCCATGGACAGAAGGAGG GCAAAGATAATATAGCAGGAACACAAAAGGAAGCTTCTACTGGAAAAGGCAGAGGGACAG AGGAAACACCAAAAAATACTTACATATAAACCTAATTAAATATGTACAAGATCTCTATGA GGAA OMIM ID 609662