Entrez gene ID | | 3384 |
Official gene symbol | | ICAM2 |
Full name | | intercellular adhesion molecule 2 |
Aliases | | ,CD102, |
Gene summary | | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17q23-q25 |
Gene position | | 62097994 - 62079955 Map Viewer |
Gene orientation | | minus |
Gene size | | 18040 bp |
Gene sequence |
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OMIM ID | | 146630 |
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