Entrez gene ID | | 3385 |
Official gene symbol | | ICAM3 |
Full name | | intercellular adhesion molecule 3 |
Aliases | | ,CD50,CDW50,ICAM-R, |
Gene summary | | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19p13.3-p13.2 |
Gene position | | 10450345 - 10444452 Map Viewer |
Gene orientation | | minus |
Gene size | | 5894 bp |
Gene sequence |
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OMIM ID | | 146631 |
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