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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IRF8 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3394
Official gene symbolIRF8
Full nameinterferon regulatory factor 8
Aliases,H-ICSBP,ICSBP,ICSBP1,IRF-8,
Gene summaryInterferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq]
LocationChromosome: 16   Locus: 16q24.1
Gene position85932774 - 85956212  Map Viewer
Gene orientationplus
Gene size23439 bp
Gene sequence
OMIM ID601565