| Entrez gene ID | | 3422 |
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| Official gene symbol | | IDI1 |
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| Full name | | isopentenyl-diphosphate delta isomerase 1 |
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| Aliases | | ,IPP1,IPPI1, |
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| Gene summary | | IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. [provided by RefSeq] |
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| Location | | Chromosome: 10 Locus: 10p15.3 |
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| Gene position | | 1095061 - 1085963 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 9099 bp |
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| Gene sequence |
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| OMIM ID | | 604055 |
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