Entrez gene ID | | 3428 |
Official gene symbol | | IFI16 |
Full name | | interferon, gamma-inducible protein 16 |
Aliases | | ,IFNGIP1,MGC9466,PYHIN2, |
Gene summary | | This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q22 |
Gene position | | 158979682 - 159024945 Map Viewer |
Gene orientation | | plus |
Gene size | | 45264 bp |
Gene sequence |
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OMIM ID | | 147586 |
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