Entrez gene ID | | 345 |
Official gene symbol | | APOC3 |
Full name | | apolipoprotein C-III |
Aliases | | ,APOCIII,MGC150353, |
Gene summary | | Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11q23.1-q23.2 |
Gene position | | 116700624 - 116703787 Map Viewer |
Gene orientation | | plus |
Gene size | | 3164 bp |
Gene sequence |
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OMIM ID | | 107720 |
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