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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IGF1R (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3480
Official gene symbolIGF1R
Full nameinsulin-like growth factor 1 receptor
Aliases,CD221,IGFIR,IGFR,JTK13,MGC142170,MGC142172,MGC18216,
Gene summaryThis receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq]
LocationChromosome: 15   Locus: 15q26.3
Gene position99192761 - 99507759  Map Viewer
Gene orientationplus
Gene size314999 bp
Gene sequence
OMIM ID147370