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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IGF2R (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3482
Official gene symbolIGF2R
Full nameinsulin-like growth factor 2 receptor
Aliases,CD222,CIMPR,M6P-R,MPR1,MPRI,
Gene summaryThe protein encoded by this gene is a receptor for both, insulin-like growth factor 2 (IGF2) and mannose 6-phosphate (M6P). The IGF2 and M6P binding sites are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of IGF2. While the mouse Igf2r gene shows exclusive expression from the maternal allele, imprinting of the human IGF2R gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele. [provided by RefSeq]
LocationChromosome: 6   Locus: 6q26
Gene position160390131 - 160527583  Map Viewer
Gene orientationplus
Gene size137453 bp
Gene sequence
OMIM ID147280