Entrez gene ID | | 353514 |
Official gene symbol | | LILRA5 |
Full name | | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 |
Aliases | | ,CD85,CD85F,ILT11,LILRB7,LIR9, |
Gene summary | | The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19q13.4 |
Gene position | | 54824409 - 54818353 Map Viewer |
Gene orientation | | minus |
Gene size | | 6057 bp |
Gene sequence |
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OMIM ID | | 606047 |