| Entrez gene ID | | 3556 |
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| Official gene symbol | | IL1RAP |
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| Full name | | interleukin 1 receptor accessory protein |
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| Aliases | | ,C3orf13,FLJ37788,IL-1RAcP,IL1R3, |
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| Gene summary | | Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq] |
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| Location | | Chromosome: 3 Locus: 3q28 |
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| Gene position | | 190231840 - 190374986 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 143147 bp |
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| Gene sequence |
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| OMIM ID | | 602626 |
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