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Gene information for IL3RA (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3563
Official gene symbolIL3RA
Full nameinterleukin 3 receptor, alpha (low affinity)
Aliases,CD123,IL3R,IL3RAY,IL3RX,IL3RY,MGC34174,hIL-3Ra,
Gene summaryThe protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. [provided by RefSeq]
LocationChromosome: X   Locus: Xp22.3 or Yp11.3
Gene position1455509 - 1501582  Map Viewer
Gene orientationplus
Gene size46074 bp
Gene sequence
OMIM ID430000