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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IL5 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3567 Official gene symbol IL5 Full name interleukin 5 (colony-stimulating factor, eosinophil) Aliases ,EDF,IL-5,TRF, Gene summary The protein encoded by this gene is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. This cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of this cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. This cytokine, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq] Location Chromosome: 5   Locus: 5q31.1 Gene position 131879214 - 131877136  Map Viewer Gene orientation minus Gene size 2079 bp Gene sequence >IL5:complement(40191008..40193086):Length=2079 ATGCACTTTCTTTGCCAAAGGCAAACGCAGAACGTTTCAGAGCCATGAGGATGCTTCTGC ATTTGAGTTTGCTAGCTCTTGGAGCTGCCTACGTGTATGCCATCCCCACAGAAATTCCCA CAAGTGCATTGGTGAAAGAGACCTTGGCACTGCTTTCTACTCATCGAACTCTGCTGATAG CCAATGAGGTAATTTTCTTTATGATTCCTACAGTCTGTAAAGTGCATAGGTAATCATTTG TGATGGTTCCTTTACTATATATAGAGATCTGTTATAAATAATAAGATTCTGAGCACATTA GTACATGGGTGATAACTACATCACCAGCAAACATTCTGTTAAAAGTTATGAATGCTGGTG TGCTGTAAAAATGATTGTATTTCCTTTCCTCTCCAGACTCTGAGGATTCCTGTTCCTGTA CATAAAAATGTAAGTTAAATTATGATTCAGTAAAATGATGGCATGAATAAGTAAATTTCC TGTTTTAAGCTGTAAATCATTAGTTATCATTGGAACTATTTAATTTTCTATATTTTGTTT TCATATGGGTGGCTGTGAATGTCTGTACTTATAAATATGAGGAATGACTTTTTATCAAGT AGAATCCTTTAAACAAGTGGATTAGGCTCTTTGGTGATGTTGTTAGTTTGCCTCCCAAAG AGCATCGTGTCAGGGATTCTTTCCAGAAGGATTCCACACTGAGTGAGAGGTGCGTGCTAG TCTCCGTGCAGTTCTGACTCTTTCTCACTCTAACGTGTTTCTGAAAGTATTAGCAACTCA GAATTATATTTTTAGAACCATGATCAGTAGACATTAAAATATATAACAAATGCCCTATAT TAATAATTTCTGCATACTTAAATAATTATGACTATATGATGGTGTTGTATGCATTTGAAT ATGTCCTGGTCATATTAAAATGTAAAATATATAGTTTTATTAGTCTAAATAGAATAAAAC TACCAGCTAGAACTGTAGAAACACATTGATATGAGTTTAATGTATAATGCATTACACTTC CAAAACATTTTTTTCCAGTTACATAATTAAGTTATATCCTTTATAAAACTCCTCAGTAAT CATATAAGCTTCATCTACTTTTTGAAAATTTTATCTTAATATGTGGTGGTTTGTTGCCTA GAAAACAAACAAAAAACTCTTTGGAGAAGGGAACTCATGTAAATACCACAAAACAAAGCC TAACTTTGTGGACCAAAATTGTTTTAATAATTATTTTTTAATTGATGAATTAAAAAGTAT ATATATTTATTGTGTACAATATGATGTTTTGAAGTATGTATACATTGCAGAATGGACAAT GGACCAAATTTTTATACCTTGTCTTGATTATTTGCATTTTAAAAATTTTCCTCATTTAGC ACCAACTGTGCACTGAAGAAATCTTTCAGGGAATAGGCACACTGGAGAGTCAAACTGTGC AAGGGGGTACTGTGGAAAGACTATTCAAAAACTTGTCCTTAATAAAGAAATACATTGACG GCCAAAAAGTAAGTTACACACATTCAATGGAAGCTATATTTGTCTGGCTGTGCCTATTTC TATGGAATTGACAGTTTCCTGTAATACCTATTGTCATTTTTCTTTTTTCACAGAAAAAGT GTGGAGAAGAAAGACGGAGAGTAAACCAATTCCTAGACTACCTGCAAGAGTTTCTTGGTG TAATGAACACCGAGTGGATAATAGAAAGTTGAGACTAAACTGGTTTGTTGCAGCCAAAGA TTTTGGAGGAGAAGGACATTTTACTGCAGTGAGAATGAGGGCCAAGAAAGAGTCAGGCCT TAATTTTCAGTATAATTTAACTTCAGAGGGAAAGTAAATATTTCAGGCATACTGACACTT TGCCAGAAAGCATAAAATTCTTAAAATATATTTCAGATATCAGAATCATTGAAGTATTTT CCTCCAGGCAAAATTGATATACTTTTTTCTTATTTAACTTAACATTCTGTAAAATGTCTG TTAACTTAATAGTATTTATGAAATGGTTAAGAATTTGGTAAATTAGTATTTATTTAATGT TATGTTGTGTTCTAATAAAACAAAAATAGACAACTGTTC OMIM ID 147850