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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IL5RA (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3568
Official gene symbolIL5RA
Full nameinterleukin 5 receptor, alpha
Aliases,CD125,CDw125,HSIL5R3,IL5R,MGC26560,
Gene summaryThe protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq]
LocationChromosome: 3   Locus: 3p26-p24
Gene position3152058 - 3111401  Map Viewer
Gene orientationminus
Gene size40658 bp
Gene sequence
OMIM ID147851