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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IL10RA (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3587
Official gene symbolIL10RA
Full nameinterleukin 10 receptor, alpha
Aliases,CDW210A,HIL-10R,IL-10R1,IL10R,
Gene summaryThe protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q23
Gene position117857106 - 117872198  Map Viewer
Gene orientationplus
Gene size15093 bp
Gene sequence
OMIM ID146933