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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TNFRSF9 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3604
Official gene symbolTNFRSF9
Full nametumor necrosis factor receptor superfamily, member 9
Aliases,4-1BB,CD137,CDw137,ILA,MGC2172,
Gene summaryThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p36
Gene position8000887 - 7979907  Map Viewer
Gene orientationminus
Gene size20981 bp
Gene sequence
OMIM ID602250