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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IMPDH2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3615 Official gene symbol IMPDH2 Full name IMP (inosine 5'-monophosphate) dehydrogenase 2 Aliases ,IMPD2,IMPDH-II, Gene summary This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq] Location Chromosome: 3   Locus: 3p21.2 Gene position 49066875 - 49061758  Map Viewer Gene orientation minus Gene size 5118 bp Gene sequence >IMPDH2:complement(49001758..49006875):Length=5118 CGAAATCGGCTGGTTTATATTGGCGCGGCCCAGACGGCAGAGGTCTCTGCGGCGCGGTCC TCGGAGACACGCGGCGGTGTCCTGTGTTGGCCATGGCCGACTACCTGATTAGTGGGGGCA CGTCCTACGTGCCAGACGACGGACTCACAGCACAGCAGCTCTTCAACTGCGGAGACGGCC TCACCTACAAGTGCGGGCCTATGGGGCTCACCTGGGCGAAGAGAGGGGCGGCACCCTGGG GAAAAGGCCAGATGGGGGCTTCCGAGAGCCGCCTTGGGCGTGGGCGTGGGGGACAGGTTT CGGGAATTGGCCACCCACCTCCGGGGCTCACTTTGAGACATCTGGAGCGGTGCTTGGGGT ACGGAGAAGCATCTCAGTAGTGCTTGGAATCTCAGGCCGGAGATTCCATGCTCCAGACAC ATGGAATTGTCAGGGTGCCAGGAGCACTGATGACAGCTCGGTGGCAGAAAAGGTCCCCTG TACCCATTTCCACCTTGTGCTGTGCCTGTGACACACAGACTCTGTCAGTGCCACTCTCTG CTCACATGCGTTACGGGTTGATTGGTACATGGGGATGGAGTCTCATGCTGCCCTAAGCTG AGAGCTTTACTCCCAATTCACTCCCTTCCCTCGCAGTGACTTTCTCATTCTCCCTGGGTA CATCGACTTCACTGCAGACCAGGTGGTGAGTATGATCAGGAATTGGGTCCTGAACATCAA GGTGAGCTAAGGTGCTACTATCACCTGGTCTCTGGGCTAACTCACCAGATTGGGCTTGGG GGTGGATTTTATAGGATCATGTTGCTTGTTAGCATGCAGGTCATACAAAAGTGCCTTTTT GTGGGGGACTCAGTAACACCTTGAGGTGTAAGGGATGCTTTCCCACACTGGTTGACGTTT GTCTCCTCAGGACCTGACTTCTGCTCTGACCAAGAAAATCACTCTTAAGACCCCACTGGT TTCCTCTCCCATGGACACAGTCACAGAGGCTGGGATGGCCATAGCAATGGCGGTGAGCCC CATGGGGTGTGGGGGAAGGAGCAAGGACTCCATCGCCTTTCCCCAAAGGCATTCAGTCCT GCTTCTTGTCACTTAGTAGTAGTCTCTTTTTATCCTGTAGCTTACAGGCGGTATTGGCTT CATCCACCACAACTGTACACCTGAATTCCAGGCCAATGAAGTTCGGAAAGTGAAGGTCAG AAGGGCAACGATCATTAGCAAGCGCTCCTGGGAATTGCACTGAGGTGGGGTGGGGTGGGA GTAGGGGTTTATTCTAATTTAGTATTCTTTCTTCCCACCATGGGGTTCAGTTACTGAGAA GACCCTGAGATTCTGTTTCTTAAAGCAGCAGCAATAGACCAGGTGTACAGTGCCTCCAGC CTACCCATGTCTCTAAGATGTGTTGGTGTGATTTGGTCTTGTGGCACTGCCAAAGGGATC GATAAGCAGAGACCCCATGCTTCAGATCAAGAGCCTGATGAAAGTAGTTCAAAGATGCGA TGCCCTTTCTCACCATCCCTTTCCAGAAATATGAACAGGGATTCATCACAGACCCTGTGG TCCTCAGCCCCAAGGATCGCGTGCGGGATGTTTTTGAGGCCAAGGCCCGGCATGGTTTCT GCGGTATCCCAATCACAGACACAGGCCGGATGGGGAGCCGCTTGGTGGGCATCATCTCCT CCAGGGACATTGATTTTCTCAAAGAGGAGGAACATGACTGTTTCTTGGAAGAGGTGGGTG CCACTGGCAGAGTAGATCCAAGCTCTAGCAGCCCAGGTTGAAGACAAGGGGCTTCTGTTG TCTAAGACATCTCTGATAGCCTCTTCTCTCTGGGAAAGGAGTGTCAAACCAAGTTTCTGA CTCCTTTATTGGGTTCCTGCATCCTTTCCCCACCAGAGGCTTTCAAACTGCCCAAATGCT TGCTAGTATTCATGCTTTGTTCTTTTAAACCCCTAAGGTAGGGGCAGTGCTTGAGGTCTG CCCTGATTTTCTTGCCATTGTTCCTGTGTTGTCCTCCTTATTCCATAGTGTAAGAGGGTG CTCCCTGTGCCATGTTGTCCTTTCTACTCATCCCTCACTCAATACCATACTGCTAAGAAT TATTGGGATCCCTTGAGGAAGGGTGTTTTGGGTGTGAATGTATGAACGTGGTGGTCCATA GAACTTCACCCCTGTAATCTCAGTACTTTGGGAGACTGAGGCAGGCAAATCATGAGGTTA GGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAA ATTAGTTGGGTGTGGTGGCGCGTGCCTCTGAGCTCAGCTACTTGGGAAGGAAAGAAAAGA GTTAACTGGTCATAGTCGATGACTGGCCCTTCTTCACATCTCACCTCCCACGTAGATAAT GACAAAGAGGGAAGACTTGGTGGTAGCCCCTGCAGGCATCACACTGAAGGAGGCAAATGA AATTCTGCAGCGCAGCAAGAAGGGTAAGTCCTAGAGCTGGGAAAGGGCCTGGAACTAATG CCTAGGGTCCTGATTCATGTCCTGCCCTGACCACAGGAAAGTTGCCCATTGTAAATGAAG ATGATGAGCTTGTGGCCATCATTGCCCGGACAGACCTGAAGAAGAATCGGGACTACCCAC TAGCCTCCAAAGATGCCAAGAAACAGCTGCTGTGTGGGGCAGCCATTGGCACTCATGAGG ATGACAAGTATAGGCTGGACTTGCTCGCCCAGGCTGGTGTGGATGTAGTGGTTTTGGTGA GCTGCTACACAGGTGGGTTGGGGCAATAGGGGCAGCTGCCACATCACAGTCTGAGACTTA CTTCTTGTCCTAGGACTCTTCCCAGGGAAATTCCATCTTCCAGATCAATATGATCAAGTA CATCAAAGACAAATACCCTAATCTCCAAGTCATTGGAGGCAATGGTAAGGCAAGATTGTG CCCTGAAGGATGTGTGGTGGGAGTGGGTAAGCTGGGCTCCCACCTTAACCTTCACATGAG CATTTTCCTTTCCTTCACCATAGTGGTCACTGCTGCCCAGGCCAAGAACCTCATTGATGC AGGTGTGGATGCCCTGCGGGTGGGCATGGGAAGTGGCTCCATCTGCATTACGCAGGAAGG TAAGAATATACTTTGATAGGGCCCACAGAGACCCCAGTTTCAGGCCCCACATACCTTGGA ACCAAGCACTCTTATGGGGACAATAGAGCCCTCCAATAGGGGCAACCCTGGGGCCAAATT GGCCTCTTGGATGGGTGACATGGCTGGAAGCAAGACAAGGTCTTGTCATCCATCACCTGC CACTCCCTTGCCTAGCCTGGCCTTCTTGCTCCTGCTCTGCACCTTCTCTAAACTCTGGTC TGTTTGTTTTATTTAGTGGCTCCCAAGATCCCTCCAGACATAAAGTCCCACAGCCCCAAA TGCCCTTCTACTGTCACGGGTTGCTATAGTAAGTCCAGCCCGGCCCACTGGCCCGGCCCA GCTGCCCACTGCCCGGCTGCTTGGTTGACGTAGCTGTAGCTCCCGGGGTTTGTGGTGCTG ATGGGTGGGCAAGGCCAACTGATACACAGACCATGGTTTGGGGGTGGTGCTCAAGAACAT AGCTCCCTCTTCCTTCTGGGGTGCTGATAGGGCAGGACCTTCTTCCCTAGGCAGGACCTT TTCTGCCCACATCTTCTGCAGTAGGCATAGTTCAGGGACCAACTCCTTTGTGTGGTCCTT GCTCTCCCACACAACCACTGCCTGCTCCACACAACCACAGCCTGCTCTCCTACACAACCA CTGCCCTTATCTTGCCTGAGCTGCCCACCATTCAGGGAGGAAGGGCTGGGCCTGACCTCA GTGCCTCTGGGGACTAACTGCACGGTGACTCCTGCCCCATCTGATACCAGCTGGACGGGG GCTTTCCCGGCTGCTAAGACTGCATGTGCCTGAGGCTGCCCTGGGCACTGCACACATGCA CGTGCACATGTGGGGGTGAGTAGAGGTCAGCACAGCTGTTTGTACTATTTAAGGCAGATG TGGCAGCAGCCATCCCAGACACGTCTGTTCCTCAGCCAAGCTGCAGTCCTGATGCAGATG TAGCCAAAAGCTCCTGGGTCCTAAATATGGCCACAGGGTCCACTGCCCGTCCCCATTAAC CCTATCCACCCATGTGTTCCTCCATCTCAACAGTGCTGGCCTGTGGGCGGCCCCAAGCAA CAGCAGTGTACAAGGTGTCAGAGTATGCACGGCGCTTTGGTGTTCCGGTCATTGCTGATG GAGGAATCCAAAATGTGGGTCATATTGCGAAAGCCTTGGCCCTTGGGGCCTCCACAGGTG AGGCCCAGTACCCGTGAAGGCCAGTGGGACCCCCTCCCTAGTGCTGCTTAGGCTCTAACC CAAGCACTCCATCTGTCCGCAGTCATGATGGGCTCTCTCCTGGCTGCCACCACTGAGGCC CCTGGTGAATACTTCTTTTCCGATGGGATCCGGCTAAAGAAATATCGCGGTATGGGTTCT CTCGATGCCATGGACAAGCACCTCAGCAGCCAGAACAGATATTTCAGGTGGGACAGGCAA GCCAGTTACCCCACCCTAATCCTGCACTGACAGTCTCATCTCTGCTGTGACCTTGCCCGT GTCTCTGCCTCTCCCTGCAGTGAAGCTGACAAAATCAAAGTGGCCCAGGGAGTGTCTGGT GCTGTGCAGGACAAAGGGTCAATCCACAAATTTGTCCCTTACCTGATTGCTGGCATCCAA CACTCATGCCAGGACATTGGTGCCAAGAGCTTGACCCAAGTCCGGTGAGCTTGGGGAGCT GGGACATGGGTAGAGGGGCTGGTCCAGGGCCAGCTACCCACATTTGACCTCTGCCCTTCT TCAGAGCCATGATGTACTCTGGGGAGCTTAAGTTTGAGAAGAGAACGTCCTCAGCCCAGG TGGAAGGTGGCGTCCATAGCCTCCATTCGTAAGTCACCCTGTCCTTGGTGGGGCCTCTGC CATACCTCATGCCTCCTTTCTCCTGCCCTCACCTCACAGGTGGTCCTTCTGCCTGCAGGT ATGAGAAGCGGCTTTTCTGAAAAGGGATCCAGCACACCTCCTCGGTTTTTTTTTCAATAA AAGTTTAGAAAGAAAAAA OMIM ID 146691