| Entrez gene ID | | 3625 |
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| Official gene symbol | | INHBB |
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| Full name | | inhibin, beta B |
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| Aliases | | ,MGC157939, |
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| Gene summary | | The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. [provided by RefSeq] |
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| Location | | Chromosome: 2 Locus: 2cen-q13 |
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| Gene position | | 121103719 - 121109383 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 5665 bp |
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| Gene sequence |
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| OMIM ID | | 147390 |
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