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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for INPP5B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3633
Official gene symbolINPP5B
Full nameinositol polyphosphate-5-phosphatase, 75kDa
Aliases,5PTase,MGC65156,MGC71303,
Gene summaryCellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p34
Gene position38412729 - 38326369  Map Viewer
Gene orientationminus
Gene size86361 bp
Gene sequence
OMIM ID147264