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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ITGAE (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3682
Official gene symbolITGAE
Full nameintegrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
Aliases,CD103,HUMINAE,MGC141996,
Gene summaryIntegrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq]
LocationChromosome: 17   Locus: 17p13
Gene position3704537 - 3617919  Map Viewer
Gene orientationminus
Gene size86619 bp
Gene sequence
OMIM ID604682