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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ITGAX (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3687
Official gene symbolITGAX
Full nameintegrin, alpha X (complement component 3 receptor 4 subunit)
Aliases,CD11C,SLEB6,
Gene summaryThis gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. [provided by RefSeq]
LocationChromosome: 16   Locus: 16p11.2
Gene position31366509 - 31394318  Map Viewer
Gene orientationplus
Gene size27810 bp
Gene sequence
OMIM ID151510