Entrez gene ID | | 3687 |
Official gene symbol | | ITGAX |
Full name | | integrin, alpha X (complement component 3 receptor 4 subunit) |
Aliases | | ,CD11C,SLEB6, |
Gene summary | | This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. [provided by RefSeq] |
Location | | Chromosome: 16 Locus: 16p11.2 |
Gene position | | 31366509 - 31394318 Map Viewer |
Gene orientation | | plus |
Gene size | | 27810 bp |
Gene sequence |
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OMIM ID | | 151510 |
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